Production Cost Report | Healthcare

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Isoniazid Production Cost Breakup From 4-cyanopyridine

Details: Germany - based plant Q2 2024  | From $ USD

This report entails the detailed cost evaluation of Isoniazid production from 4-cyanopyridine. Initially, 4-cyanopyridine is hydrolyzed in a mixture of methanol and water with aqueous sodium hydroxide. This is followed by a reaction with hydrazine hydrate, resulting in isoniazid production with an overall conversion rate over 96% and it takes around 21 minutes for the entire two-staged process.

Top Manufacturers of Isoniazid

  • AMSAL CHEM
  • Camus pharma
  • Titan Pharma (India)
  • Taizhou Tianrui Pharmaceutical
  • Resonance Specialties
  • Calyx Pharma & Chem

Feedstock for Isoniazid

The feedstock for isoniazid primarily includes 4-cyanopyridine, a nitrile compound crucial for its synthesis, along with other compounds like hydrazine hydrate and methanol. Proper storage and consistent availability are essential to procure these key ingredients from chemical suppliers. The production of these feedstocks along with price, demand fluctuation and supply chain management directly influence the procurement of isoniazid. Effective procurement strategies, keeping in check the government, pharmaceutical and healthcare policies, are vital to maintaining steady production and global healthcare demands.

The project economic analysis provided in the report discusses a Germany-based plant:

  • Manufacturing Process
    • Process Flow
    • Material Flow
    • Material Balance
  • Raw Material and Product's Specifications
    • Raw Material Consumption
    • Product and Co-Product Generation
    • Capital Investment
  • Land and Site Cost
    • Offsites/Civil Works
    • Equipment Cost
    • Auxiliary Equipment Cost
    • Contingency
    • Engineering and Consulting Charges
    • Working Capital
  • Variable Cost
    • Raw Material
    • Utilities
  • Fixed Cost
    • Labor Requirement & Wages
    • Overhead Expenses
    • Maintenance Charges
  • Financing Costs
    • Interest on Working Capital
    • Interest on Loans
  • Depreciation Charges
  • General Sales and Admin Costs
  • Production Cost Summary
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Report Content

Key Process Information

Evaluation of significant technical parameters along with process descriptions such as:

  • Consumption of Raw Material
  • Product Creation
  • Block Flow Diagram
  • Description of the Manufacturing Facility

Utilities Consumption

Evaluation of utilities consumed during the entire process based on:

  • Consumption per unit of product generated
  • Utility cost split and share of each utility in the total cost

Process Flow Diagram

Representation of various operations involved including:

  • Step-wise process
  • Utility consumption in each operation

Capital Cost Analysis

In-depth analysis of costs involved in setting up a new manufacturing unit, including:

  • Cost of Building a Process Unit
  • Cost of Setting Up the Infrastructure
  • Working Capital
  • Commissioning & Start-Up of the Plant

Implementation Schedule

Time frame of the project design, which includes:

  • Plant Start-Up
  • Plant Construction
  • Engineering Fundamentals
  • Raw Material Procurement

Construction Cost Details

Detailed analysis of costs involved in the operation of various functional units in the process unit and infrastructure.

Operating Cost Analysis

Evaluation of costs associated with the production of the final product, namely:

  • Procurement of Raw Materials
  • Consumption of Utilities
  • Fixed Costs
  • Depreciation

Economic Analysis

Analysis of the way in which process economics are impacted by plant capacity.

  • Construction Cost
  • Working Capital
  • Fixed and Variable Operating Costs
  • Corporate Overhead
  • Depreciation

Customized Analyses

Detailed cost estimates of any industrial plant depending on your requirements, including plant capacity and location as per the need.

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