Esmolol Production Cost Reports
Healthcare
The report provides a detailed analysis essential for establishing an Esmolol manufacturing plant. It encompasses all critical aspects necessary for Esmolol production, including the cost of Esmolol production, Esmolol plant cost, Esmolol production costs, and the overall Esmolol manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating an Esmolol production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Esmolol is a medication used to quickly control the heart rate in patients with atrial fibrillation or atrial flutter that occurs during or after surgery or in other urgent situations where short-term control of the heart rate with a fast-acting drug is needed. It can also be used to treat a rapid heartbeat that is not caused by a compensatory mechanism, such as exercise or fever, and requires specific intervention. It is a beta-adrenergic blocker that is cardioselective.
The procurement of Esmolol is influenced by its application in the pharmaceutical and medical industries. The use of Esmolol has been demanded more since cases of cardiovascular diseases are rising. For focal atrial tachycardia, Esmolol is an effective emergency drug, especially in patients with an active bronchospasm. Furthermore, because of its brief half-life, Esmolol has been shown to be a reliable and effective medicine for regulating blood pressure during surgery. The medication is also recommended for sinus tachycardia, a condition in which an abnormally fast heartbeat necessitates prompt medical attention, particularly in situations of acute coronary syndrome.
Aortic dissection, acute coronary syndrome, non-ST elevation myocardial infarction, hypertensive emergencies, thyrotoxicosis, refractory ventricular tachycardia, ventricular fibrillation resistant to defibrillation, and mitigating the catecholamine response during electroconvulsive therapy are among the conditions for which this medication is used off-label to manage rate and rhythm, thus increasing its demand. Overall, industrial Esmolol procurement is influenced by its application in the pharmaceutical and medical industries, rising cases of cardiovascular diseases, its off-label uses, fewer side effects, emergency uses, and regulatory approvals.
Raw Material for Esmolol Production
According to the Esmolol manufacturing plant project report, the key raw material used in the production of Esmolol includes 4-hydroxybenzaldehyde.
Manufacturing Process of Esmolol
The extensive Esmolol production cost report consists of the following major industrial manufacturing process:
- Production from 4-hydroxybenzaldehyde: The manufacturing process of Esmolol starts with the Wittig reaction of the starting compound to form an intermediate. The intermediate reacts with Pd/C in ethyl acetate under a hydrogen atmosphere to form another intermediate. The intermediate is treated with epichlorohydrin in the presence of K2CO3 in acetonitrile at reflux condition to form the racemic epoxide of methyl 3-[4-(oxiran-2-ylmethoxy)-phenyl] propanoate. The racemic epoxide is then reacted with Jacobsen catalyst and water to form enantioselective epoxide of the final intermediate. Finally, the compound is reacted with N-isopropyl amine in the presence of water to produce Esmolol.
Esmolol, commercially known as Brevibloc, is a white to off-white crystalline powder having the molecular formula C16H25NO4 and a molecular weight of 295.37 g/mol. It has a water solubility of 0.144 mg/mL. It has a log P value of 1.7. It is usually available in its hydrochloride form. The value of its dissociation constant, pKa, is 14.09. It is a beta-adrenergic blocker used to treat hypertension and perioperative tachycardia, among other forms of tachycardia, by temporarily regulating heart rate and ventricular rhythm.
Product Details
| Particulars | Details |
|---|---|
| Product Name | Esmolol |
| Scope | Manufacturing Process: Process Flow, Material Flow, Material Balance Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital Variable Cost: Raw Material, Utilities, Other Variable Costs Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs Financing Costs: Interest on Working Capital, Interest on Loans Other Costs: Depreciation Charges, General Sales and Admin Cost |
| Currency | US$ (Data can also be provided in the local currency) |
| Pricing and Purchase Options | Basic: US$ 2499 Premium: US$ 3499 Enterprise: US$ 4799 |
| Customization Scope | The report can be customized as per the requirement of the customer |
| Post-Sale Analysts Report | 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable |
| Delivery Format | PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request) |
How does our Esmolol Production Cost Report Provide Exhaustive Data and Extensive Insights?
At Procurement Resource, we not only focus on optimizing the should cost of production for Esmolol but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.
We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Esmolol market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.
Key Questions Answered in This Report
- What are the key requirements for setting up an Esmolol manufacturing plant?
- How is Esmolol manufactured?
- What is the process flow involved in producing Esmolol?
- What are the raw material requirements and costs for producing Esmolol?
- What is the total size of land required for setting up an Esmolol manufacturing plant?
- What are the construction requirements for setting up an Esmolol manufacturing plant?
- What are the machinery requirements for producing Esmolol?
- What are the utility requirements and costs for producing Esmolol?
- What are the manpower requirements for producing Esmolol?
- What are the average salaries/wages of manpower working in an Esmolol manufacturing plant?
- What are the packaging requirements and associated costs for Esmolol?
- What are the transportation requirements and associated costs for Esmolol?
- What are the capital costs for setting up an Esmolol manufacturing plant?
- What are the operating costs for setting up an Esmolol manufacturing plant?
- What should be the price of Esmolol?
- What will be the income and expenditures for an Esmolol manufacturing plant?
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