Pravastatin Production Cost Reports

The report provides a detailed analysis essential for establishing a Pravastatin manufacturing plant. It encompasses all critical aspects necessary for Pravastatin production, including the cost of Pravastatin production, Pravastatin plant cost, Pravastatin production costs, and the overall Pravastatin manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Pravastatin production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Pravastatin is a medication primarily used to manage cholesterol levels and reduce occurrence of heart disorders.  It works by blocking an enzyme in the liver that produces cholesterol that, in turn, reduces levels of bad cholesterol and increases good cholesterol. It is used for treating primary hypercholesterolemia that is caused by increased levels of LDL cholesterol in the blood. It is also utilized in managing mixed dyslipidemia that is because of high LDL cholesterol and triglycerides. Pravastatin is employed in preventing cardiac events in patients who already have coronary artery disease. It reduces the episodes of non-fatal heart attacks and even deaths due to heart disease. It can be used for children above eight years to manage heterozygous familial hypercholesterolemia.

The pravastatin market is driven by several key factors. Its use in managing cardiovascular health, by cholesterol management, contributes to its growing demand. Its use in treating cholesterol-related problems such as hypercholesterolemia, mixed dyslipidemia, etc., makes it a popular medication in the clinical field. Its usage in children above eight years for treating genetic cholesterol problems makes it a useful medicine for a wide range of patients. Overall, industrial Pravastatin procurement is influenced by its increasing demand for treating cholesterol-related in both adults and children, along with advancements in pharmaceutical research, emerging economies leading to affordable medications, combination therapies and market accessibility.

Raw Material for Pravastatin Production

According to the Pravastatin manufacturing plant project report, the key raw materials used in the production of Pravastatin include Penicillium Chrysogenum-Penicillium Citrinum-Bacterium Enzyme.

Manufacturing Process of Pravastatin

The extensive Pravastatin production cost report consists of the following major industrial manufacturing process:

1. From Penicillium chrysogenum, Penicillium citrinum, and Bacterium Enzyme: The manufacturing process for Pravastatin involves several key steps. First, the fungus Penicillium chrysogenum is introduced with genes of Penicillium citrinum that form compactin in large amounts. After that, another bacterium enzyme is introduced that forms Pravastatin. The final product is separated and purified to obtain pure Pravastatin.

Pravastatin is a white color solid. Its molecular formula is C23H36O7, and it has a molecular mass of 424.534 g/mol. It is solid at room temperature having a melting point in range 171.2 - 173°C and a boiling point over 600°C. It is moderately soluble in water, and it is a 3-hydroxy carboxylic acid and acts as a reversible competitive inhibitor of the enzyme responsible for the rate-limiting step in cholesterol biosynthesis. Its oral bioavailability ranges from 17% to 34%, having peak plasma concentrations occurring 1 to 1.5 hours. Its plasma half-life is about 1.8 hours, but the active metabolite can remain in circulation for up to 77 hours. All these physical and chemical properties contribute to its cholesterol-lowering effects.