Dipyridamole Production From 5-Niroorotic Acid
Production Cost Report | Healthcare
Details: Germany - based plant Q2 2024 | From $ USD
This report entails the detailed cost evaluation of dipyridamole production from 5-nirrorotic acid. The preparation process is initiated by nitrating 2,4-dihydroxy-6-methylpyrimidine, which yields 5-nitroaromatic acid. The reaction is processed by reducing 5-nitroorotic acid, resulting in 5-aminoorotic acid, which is then reacted with urea or potassium cyanide to give 2,4,6,8-tetrahydroxypyrimido[5,4-d] pyrimidine, as a product.
It is then reacted with a mixture of phosphorous oxychloride and phosphorous pentachloride that leads to the formation of 2,4,6,8- tetra-chloropyrimido[5,4-d] pyrimidine as an intermediate. The intermediate is then treated with piperidine, yielding 2,6-dichloropyrimido-4,8-dipiperidino[5,4-d] pyrimidine as a resultant compound, which again reacts with diethanolamine to produce dipyridamole as the final product.
Top Producers of Dipyridamole
- Glenmark Pharma
- Dr. Reddy's Lab
- AnazaoHealth Corporation
- Pro Doc Limitee
- Hikma Pharmaceuticals
Feedstock for Dipyridamole
Dipyridamole is an antiplatelet medication produced from 5-nitroaromatic acid as its primary feedstock. The procurement of dipyridamole is influenced by various factors, including the production cost and processing of its raw materials (including urea, acetoacetic ether, etc., for 2,4-dihydroxy-6-methylpyrimidine, which is then used to yield 5-nitroaromatic acid), its supply chain stability, as well as the logistics and trading activities, etc.
Moreover, other prominent factors such as the demand observed for dipyridamole as an antiplatelet drug in healthcare and pharmaceutical industries, the variations in its market prices, transportation and distribution operations, demand from various countries (including North America, Europe, Latin America, etc.), and governmental policies strongly govern its procurement.
The project economic analysis provided in the report discusses a Germany-based plant:
- Manufacturing Process
- Process Flow
- Material Flow
- Material Balance
- Raw Material and Product's Specifications
- Raw Material Consumption
- Product and Co-Product Generation
- Capital Investment
- Land and Site Cost
- Offsites/Civil Works
- Equipment Cost
- Auxiliary Equipment Cost
- Contingency
- Engineering and Consulting Charges
- Working Capital
- Variable Cost
- Raw Material
- Utilities
- Fixed Cost
- Labor Requirement & Wages
- Overhead Expenses
- Maintenance Charges
- Financing Costs
- Interest on Working Capital
- Interest on Loans
- Depreciation Charges
- General Sales and Admin Costs
- Production Cost Summary
Report Content
Key Process Information
Evaluation of significant technical parameters along with process descriptions such as:
- Consumption of Raw Material
- Product Creation
- Block Flow Diagram
- Description of the Manufacturing Facility
Utilities Consumption
Evaluation of utilities consumed during the entire process based on:
- Consumption per unit of product generated
- Utility cost split and share of each utility in the total cost
Process Flow Diagram
Representation of various operations involved including:
- Step-wise process
- Utility consumption in each operation
Capital Cost Analysis
In-depth analysis of costs involved in setting up a new manufacturing unit, including:
- Cost of Building a Process Unit
- Cost of Setting Up the Infrastructure
- Working Capital
- Commissioning & Start-Up of the Plant
Implementation Schedule
Time frame of the project design, which includes:
- Plant Start-Up
- Plant Construction
- Engineering Fundamentals
- Raw Material Procurement
Construction Cost Details
Detailed analysis of costs involved in the operation of various functional units in the process unit and infrastructure.
Operating Cost Analysis
Evaluation of costs associated with the production of the final product, namely:
- Procurement of Raw Materials
- Consumption of Utilities
- Fixed Costs
- Depreciation
Economic Analysis
Analysis of the way in which process economics are impacted by plant capacity.
- Construction Cost
- Working Capital
- Fixed and Variable Operating Costs
- Corporate Overhead
- Depreciation
Customized Analyses
Detailed cost estimates of any industrial plant depending on your requirements, including plant capacity and location as per the need.
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