Production Cost Report | Healthcare

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Hydrochlorothiazide Production Cost Breakup From Para-Formaldehyde

Details: Germany - based plant Q2 2024  | From $ USD

This report provides an extensive cost evaluation of hydrochlorothiazide production from para-formaldehyde. Hydrochlorothiazide can be produced either in nonaqueous media or in aqueous alkaline solution. In nonaqueous media, its synthesis involves the reaction of para-formaldehyde with 5-chloro-2,4-disulfamoylaniline. In aqueous alkaline solution, its synthesis takes place by the reaction of formaldehyde with chlorothiazide.

Top Produers For Hydrochlorothiazide

  • PLIVA
  • Ipca Labs.
  • Blue Circle Organics 
  • Shaoxing Hantai Pharma 

Feedstock For Hydrochlorothiazide

The feedstock for hydrochlorothiazide, concerning procurement, comprises the essential raw materials and chemicals such as formaldehyde, chlorothiazide and 5-chloro-2,4-disulfamoylaniline necessary for its production. Procuring these materials is crucial to ensure an uninterrupted supply chain to produce hydrochlorothiazide.

The procurement process for these feedstocks involves identifying reliable suppliers that can ensure purity of feedstock at a competitive price. Moreover,  effective procurement of feedstock for hydrochlorothiazide is essential for maintaining a smooth and efficient production process, meeting market demand, and ensuring the availability of this vital medication for patients with hypertension and other medical conditions. Price, market, or demand fluctuation in the chemical industry manufacturing these feedstocks directly impacts the procurement of hydrochlorothiazide all over the world.

The project economic analysis provided in the report discusses a Germany-based plant:

  • Manufacturing Process
    • Process Flow
    • Material Flow
    • Material Balance
  • Raw Material and Product's Specifications
    • Raw Material Consumption
    • Product and Co-Product Generation
    • Capital Investment
  • Land and Site Cost
    • Offsites/Civil Works
    • Equipment Cost
    • Auxiliary Equipment Cost
    • Contingency
    • Engineering and Consulting Charges
    • Working Capital
  • Variable Cost
    • Raw Material
    • Utilities
  • Fixed Cost
    • Labor Requirement & Wages
    • Overhead Expenses
    • Maintenance Charges
  • Financing Costs
    • Interest on Working Capital
    • Interest on Loans
  • Depreciation Charges
  • General Sales and Admin Costs
  • Production Cost Summary
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Report Content

Key Process Information

Evaluation of significant technical parameters along with process descriptions such as:

  • Consumption of Raw Material
  • Product Creation
  • Block Flow Diagram
  • Description of the Manufacturing Facility

Utilities Consumption

Evaluation of utilities consumed during the entire process based on:

  • Consumption per unit of product generated
  • Utility cost split and share of each utility in the total cost

Process Flow Diagram

Representation of various operations involved including:

  • Step-wise process
  • Utility consumption in each operation

Capital Cost Analysis

In-depth analysis of costs involved in setting up a new manufacturing unit, including:

  • Cost of Building a Process Unit
  • Cost of Setting Up the Infrastructure
  • Working Capital
  • Commissioning & Start-Up of the Plant

Implementation Schedule

Time frame of the project design, which includes:

  • Plant Start-Up
  • Plant Construction
  • Engineering Fundamentals
  • Raw Material Procurement

Construction Cost Details

Detailed analysis of costs involved in the operation of various functional units in the process unit and infrastructure.

Operating Cost Analysis

Evaluation of costs associated with the production of the final product, namely:

  • Procurement of Raw Materials
  • Consumption of Utilities
  • Fixed Costs
  • Depreciation

Economic Analysis

Analysis of the way in which process economics are impacted by plant capacity.

  • Construction Cost
  • Working Capital
  • Fixed and Variable Operating Costs
  • Corporate Overhead
  • Depreciation

Customized Analyses

Detailed cost estimates of any industrial plant depending on your requirements, including plant capacity and location as per the need.

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