Ivermectin Production by Hydrogenation Reaction
Production Cost Report | Healthcare
Details: Germany - based plant Q2 2024 | From $ USD
This report entails the detailed cost evaluation of ivermectin production by hydrogenation reaction. The preparation process begins by fermenting Streptomyces avermitilis, a soil bacterium, by culturing it in carbon and nitrogen sources (including glycerol, starch, glucose, casein, nitrate, etc.). The process is further carried out by extraction and purification, leading to the formation of avermectin as an intermediate. The intermediate is further hydrogenated in the presence of a catalyst, i.e., chlorotic (triphenylphosphine) rhodium(I). The process results in the production of ivermectin as the final product.
Top Producers of Ivermectin
- HuBei YuanCheng SaiChuang
- MERCK
- Hero Pharmaceutical
- LAND
Feedstock for Ivermectin
Ivermectin is an antibiotic prepared by fermenting Streptomyces avermitilis bacterium. The nitrogen and carbon sources (including glucose, starch, glycerol, casein, etc.) used for the fermentation of Streptomyces avermitilis serve as the primary feedstocks for ivermectin. The procurement of ivermectin is majorly dependent upon some of the crucial factors, including the availability of its raw materials (including casein, starch, glycerol, etc.), production and processing cost of ivermectin, variations in the market prices and governmental policies, etc. Additionally, other factors, including the demand for ivermectin in the pharmaceutical and healthcare sectors, supply chain stability, trade and transportation activities, and financial conditions, significantly determine its procurement globally.
The project economic analysis provided in the report discusses a Germany-based plant:
- Manufacturing Process
- Process Flow
- Material Flow
- Material Balance
- Raw Material and Product's Specifications
- Raw Material Consumption
- Product and Co-Product Generation
- Capital Investment
- Land and Site Cost
- Offsites/Civil Works
- Equipment Cost
- Auxiliary Equipment Cost
- Contingency
- Engineering and Consulting Charges
- Working Capital
- Variable Cost
- Raw Material
- Utilities
- Fixed Cost
- Labor Requirement & Wages
- Overhead Expenses
- Maintenance Charges
- Financing Costs
- Interest on Working Capital
- Interest on Loans
- Depreciation Charges
- General Sales and Admin Costs
- Production Cost Summary
Report Content
Key Process Information
Evaluation of significant technical parameters along with process descriptions such as:
- Consumption of Raw Material
- Product Creation
- Block Flow Diagram
- Description of the Manufacturing Facility
Utilities Consumption
Evaluation of utilities consumed during the entire process based on:
- Consumption per unit of product generated
- Utility cost split and share of each utility in the total cost
Process Flow Diagram
Representation of various operations involved including:
- Step-wise process
- Utility consumption in each operation
Capital Cost Analysis
In-depth analysis of costs involved in setting up a new manufacturing unit, including:
- Cost of Building a Process Unit
- Cost of Setting Up the Infrastructure
- Working Capital
- Commissioning & Start-Up of the Plant
Implementation Schedule
Time frame of the project design, which includes:
- Plant Start-Up
- Plant Construction
- Engineering Fundamentals
- Raw Material Procurement
Construction Cost Details
Detailed analysis of costs involved in the operation of various functional units in the process unit and infrastructure.
Operating Cost Analysis
Evaluation of costs associated with the production of the final product, namely:
- Procurement of Raw Materials
- Consumption of Utilities
- Fixed Costs
- Depreciation
Economic Analysis
Analysis of the way in which process economics are impacted by plant capacity.
- Construction Cost
- Working Capital
- Fixed and Variable Operating Costs
- Corporate Overhead
- Depreciation
Customized Analyses
Detailed cost estimates of any industrial plant depending on your requirements, including plant capacity and location as per the need.
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