Ampicillin Production Cost Reports

The report provides a detailed analysis essential for establishing an ampicillin manufacturing plant. It encompasses all critical aspects necessary for ampicillin production, including the cost of ampicillin production, ampicillin plant cost, ampicillin production costs, and the overall ampicillin manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating an ampicillin production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Ampicillin is a bactericidal substance that is frequently used in pharmaceutical applications and is renowned to be an antibiotic medication. It is a prevalent antibiotic used to treat specific bacterial infections by inhibiting bacterial growth in the affected area.

It belongs to the penicillin drug family, commonly prescribed to address infections such as meningitis, pneumonia, gonorrhea, bladder infections, throat infections, gastrointestinal tract infections, urinary tract infections, infections of the reproductive organs, lung infections, sinus infections, and more.

The market for ampicillin is majorly driven by its applications for the treatment of genitourinary tract infection, gastrointestinal infection, meningitis, respiratory tract infection, lung infections, etc., which propels its demand in the pharmaceutical industry. Thus, it is widely utilized as a bactericidal medication used to treat and manage certain bacterial infections.

Due to its property of acid resistance, it can also be administered orally, which further accentuates its demand in the medical sector. Additionally, several factors influence an industrial ampicillin procurement, such as the availability and cost of production of ampicillin’s feedstock (Penicillin, 6-amino penicillanic acid, etc), ampicillin market prices, distribution (including trading and shipping), logistics, environmental regulations, safety standards, etc.

Raw Material for Ampicillin Production

According to the Ampicillin manufacturing plant project report, the major raw materials for Ampicillin production include 6-Aminopenicillanic Acid - D-(-)- α-Phenylglycine.

Manufacturing Process of Ampicillin

The extensive Ampicillin production cost report consists of the following industrial manufacturing processes:

• Production Process of Ampicillin from Penicillin: This method involves enzymatic process in a reactor which begins with the formation of 6-Amino penicillanic Acid by using potassium salt of penicillin G/V. Further, the product from the reactor is crystallized and filtered, and washed with suitable solvents, followed by its packing after being dried.
• Production Process of Ampicillin from 6-Amino Penicillanic Acid and D(-) alpha-phenylglycine Chloride Hydrochloride: This method involves silylation of 6-amino penicillanic acid (6-APA) in a suitable solvent and in the presence of a catalyst. Then, 6-APA is condensed with D(-) alpha-phenylo glycine chloride hydrochloride in the presence of a base, resulting in the formation of ampicillin trihydrate cystals. Further, sodium hydrozide solution is added to the ampicillin trihydrate, which gives ampicillin sodium. After filtration, ampicillin sodium dried powder is sieved and packed.

Ampicillin is a chemical compound referred to as an antibiotic drug, primarily associated with pharmaceutical activities. It is derived from penicillin through a chemical synthesis process to create the commercial drug known as Ampicillin. This solid chemical compound appears white in color and is commonly found in a crystalline form.

It is odorless but may possess a faint characteristic odor similar to that of penicillin. The compound is derived from penicillin, resulting in the formation of Ampicillin trihydrate, Ampicillin anhydrous, and Ampicillin sodium – the major commercial forms of Ampicillin drugs. The stability of Ampicillin sodium is inversely related to the concentration of the solution.

The drug appears to be susceptible to inactivation in solutions containing dextrose and exhibits a catalytic effect during hydrolysis. In terms of solubility, it readily dissolves in water and a few specific chemical solvents, including dimethyl sulfoxide, methanol, ethanol, and dimethylacetamide. Conversely, the compound is insoluble in ether, benzene, and chloroform, and it melts at a temperature of 208°C.