Antipyrine Production Cost Reports

The report provides a detailed analysis essential for establishing an Antipyrine manufacturing plant. It encompasses all critical aspects necessary for Antipyrine production, including the cost of Antipyrine production, Antipyrine plant cost, Antipyrine production costs, and the overall Antipyrine manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating an Antipyrine production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
 
Antipyrine or Phenazone is a non-steroidal anti-inflammatory drug (NSAID) that finds various applications in the pharmaceutical industry. It is widely used as an analgesic for relieving inflammation, pain, and fever. It also finds its application in combination with other medications like benzocaine in otic solutions for alleviating the symptoms of acute otitis media. It is also used to alleviate swelling and pain caused by middle ear infections. It is also utilized in analyzing the effects of other drugs or diseases on enzymes that metabolize drugs in the liver.

The demand for Antipyrine is primarily driven by its application as an oral drug in the treatment of various types of ear infections, which also promotes its market growth. Its application as an analgesic and antipyretic for the treatment of fever, pain, and inflammation further enhances its demand in the medical and healthcare industries. Its usage as an oral drug or ear drops in combination with other medications in alleviating the symptoms of pain and swelling in the ear due to certain infections also contributes to its demand in the pharmaceutical industry. Antipyrine, like many other pharmaceutical compounds, is subject to strict regulatory controls. Therefore, compliance with strict regulatory requirements of different countries, such as the FDA in the United States or the EMA in Europe, directly impacts industrial Antipyrine procurement. Disruptions in the supply chain due to numerous factors like geopolitical issues, trade restrictions, or natural disasters also greatly impact the availability and cost of Antipyrine. Additionally, changes in the supply, cost, and availability of high-quality raw materials, including phenylhydrazine and ethyl acetoacetate, also affect the procurement strategies for Antipyrine.

Raw Material for Antipyrine Production

According to the Antipyrine manufacturing plant project report, the major raw materials for Antipyrine production include Phenylhydrazine-Ethyl Acetoacetate.

Manufacturing Process of Antipyrine

The extensive Antipyrine production cost report consists of the following industrial manufacturing process:

• Production from Phenylhydrazine: This method of production involves the synthesis of Antipyrine by using phenylhydrazine and ethyl acetoacetate as the starting materials. The synthesis begins with the mixing of phenylhydrazine and ethyl acetoacetate to form an intermediate compound. Further, the intermediate compound undergoes methylation by using dimethyl sulfate or methyl iodide in acetonitrile, followed by re-crystallization to synthesize crystals of antipyrine as the final product.

Antipyrine is a chemical compound that is a derivative of pyrazolone. It serves as an analgesic and antipyretic that is given by mouth and in the form of ear drops. The compound is also known as Phenazone or Antipyrine. The chemical formula of the compound is C11H12N2O. Its molecular weight is 188.23 g/mol. The IUPAC name of the compound is 1,5-dimethyl-2-phenylpyrazol-3-one. It appears as a white powder or colorless crystals. The boiling point of the compound is 319 °C, and its melting point is around 114 °C. It has a good solubility in water, which is around 51900 mg/L (at 25 °C). Its value of Log P is 0.38, and its pka value is 1.4. Also, the compound consists of a five-membered lactam pyrazolone heterocyclic ring as a pharmacophore segment.