Aztreonam Production Cost Reports
Healthcare
The report provides a detailed analysis essential for establishing an Aztreonam manufacturing plant. It encompasses all critical aspects necessary for Aztreonam production, including the cost of Aztreonam production, Aztreonam plant cost, Aztreonam production costs, and the overall Aztreonam manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating an Aztreonam production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Aztreonam is a broadly prescribed antibiotic used to treat infections such as septicemia, lower respiratory tract infections, gynecologic infections, skin and skin structure infections, urinary tract infections, and intra-abdominal infections caused by certain types of gram-negative bacteria. This drug belongs to the beta-lactam family. The first discovery was made from a Chromobacterium violaceum bacterium. It works by attaching itself to penicillin-binding proteins, which prevents the formation of cell walls and slows down bacterial growth.
The procurement of Aztreonam is influenced by its use in pharmaceutical and medical industries as an antibiotic to treat various bacterial infections. The rising cases of bacterial infections is increasing the demand for Aztreonam. It is not affected by beta-lactamase, the enzyme that destroys many other antibiotics, which therefore allows it to target certain types of bacteria, especially those causing infection in the meninges, bladder and kidneys hence increasing its market attractiveness.
The general availability of generic versions of Aztreonam has also increased the size of its market by giving choices, thereby reaching out to a greater population of patients and healthcare providers. Furthermore, Aztreonam remains popular since it is available both for injection and inhalation allowing physicians make a choice on how to handle definite infections, thus promoting its market appeal. Overall, industrial Aztreonam procurement is influenced by its utilization in the pharmaceutical and medical industries as an antibiotic, rising cases of bacterial infections, resistance to beta-lactamase, availability in generic versions and various dosage forms, and regulatory approvals.
Raw Material for Aztreonam Production
According to the Aztreonam manufacturing plant project report, the key raw material used in the production of Aztreonam includes (tert-butoxycarbonyl)-l-Allothreonine.
Manufacturing Process of Aztreonam
The extensive Aztreonam production cost report consists of the following major industrial manufacturing process:
- Production from (tert-butoxycarbonyl)-l-Allothreonine: The manufacturing process of Aztreonam starts with the reaction of the starting compound with O-benzylhydroxylamine in the presence of HOBt (1-hydroxybenzotriazole) and DCCI (dicyclohexylcarbodiimide) in THF to form an amide. The amide undergoes cyclization in the presence of PPh3 and diethyl azodiformate in THF to give β-lactam. The compound is subjected to reduction by H2 catalyzed by Pd/C in ethanol to form an intermediate. The intermediate undergoes reduction in the presence of TiCl3 in methanol to give another intermediate. The intermediate is subjected to hydrolysis and is reacted with benzyl chloroformate to give the third intermediate. The intermediate undergoes sulfonation with SO3 in DMF, and further treatment of the resulting product with tetrabutylammonium sulfate in DCM gives the sulfonic acid tetrabutylammonium salt. The compound undergoes debenzylation with H2 catalyzed by Pd/C in DMF to form an intermediate. The intermediate is subjected to condensation with the acetic acid in acetone to give the final intermediate. Finally, the intermediate undergoes hydrolyzation with trifluoroacetic acid to produce Aztreonam.
Aztreonam, commercially known as Azactam, is a white to pale yellow crystalline powder having the molecular formula C13H17N5O8S2 and a molecular weight of 435.4 g/mol. It is almost insoluble in water, with an estimated water solubility of 0.0429 mg/mL. It has a log P value of 0.04. The value of its dissociation constant, pKa, is 3.91. It is a monocyclic beta-lactam antibiotic used to treat various bacterial infections.
Product Details
| Particulars | Details |
|---|---|
| Product Name | Aztreonam |
| Scope | Manufacturing Process: Process Flow, Material Flow, Material Balance Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital Variable Cost: Raw Material, Utilities, Other Variable Costs Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs Financing Costs: Interest on Working Capital, Interest on Loans Other Costs: Depreciation Charges, General Sales and Admin Cost |
| Currency | US$ (Data can also be provided in the local currency) |
| Pricing and Purchase Options | Basic: US$ 2499 Premium: US$ 3499 Enterprise: US$ 4799 |
| Customization Scope | The report can be customized as per the requirement of the customer |
| Post-Sale Analysts Report | 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable |
| Delivery Format | PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request) |
How does our Aztreonam Production Cost Report Provide Exhaustive Data and Extensive Insights?
At Procurement Resource, we not only focus on optimizing the should cost of production for Aztreonam but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.
We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Aztreonam market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.
Key Questions Answered in This Report
- What are the key requirements for setting up an Aztreonam manufacturing plant?
- How is Aztreonam manufactured?
- What is the process flow involved in producing Aztreonam?
- What are the raw material requirements and costs for producing Aztreonam?
- What is the total size of land required for setting up an Aztreonam manufacturing plant?
- What are the construction requirements for setting up an Aztreonam manufacturing plant?
- What are the machinery requirements for producing Aztreonam?
- What are the utility requirements and costs for producing Aztreonam?
- What are the manpower requirements for producing Aztreonam?
- What are the average salaries/wages of manpower working in an Aztreonam manufacturing plant?
- What are the packaging requirements and associated costs for Aztreonam?
- What are the transportation requirements and associated costs for Aztreonam?
- What are the capital costs for setting up an Aztreonam manufacturing plant?
- What are the operating costs for setting up an Aztreonam manufacturing plant?
- What should be the price of Aztreonam?
- What will be the income and expenditures for an Aztreonam manufacturing plant?
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