Bumetanide Production Cost Reports

Healthcare

The report provides a detailed analysis essential for establishing a Bumetanide manufacturing plant. It encompasses all critical aspects necessary for Bumetanide production, including the cost of Bumetanide production, Bumetanide plant cost, Bumetanide production costs, and the overall Bumetanide manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Bumetanide production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Bumetanide is a sulfamyl diuretic that is used to treat nephrotic syndrome, liver and renal disease, and edema associated with congestive heart failure. Its physiological action is to increase the diuresis at the loop of Henle; thus, it belongs to the category of loop diuretic. The medication can also be used off-label to treat acute hypercalcemia.

The procurement of Bumetanide is influenced by its application in the pharmaceutical and medical industries as a diuretic. The demand for Bumetanide is also increasing due to the rising cases of heart failure, liver cirrhosis, and chronic kidney disease. It witnesses a significant demand from the aging population as they are more likely to be affected by conditions such as heart and renal diseases. Additionally, refractory edema that is resistant to other loop diuretics may benefit from it, thus increasing its demand.

It may be used alone or with other antihypertensive medications in treating hypertension. Bumetanide may be a viable choice for people who have an adverse reaction to furosemide, another loop diuretic. The medication can also be used off-label to treat acute hypercalcemia. In general, industrial Bumetanide procurement is influenced by its application in the pharmaceutical and medical industries as a diuretic to treat heart and renal diseases, the rising cases of heart and renal diseases, the aging population, fewer side effects, better tolerability, its off-label uses, its wide range of applications, its usage with other diuretics, increasing healthcare awareness among people, cost-efficiency, rising technological advancements, research & development, and regulatory approvals.

Raw Material for Bumetanide Production

According to the Bumetanide manufacturing plant project report, the key raw material used in the production of Bumetanide includes 4-chlorobenzoic acid.

Manufacturing Process of Bumetanide

The extensive Bumetanide production cost report consists of the following major industrial manufacturing process:

  • Production from 4-chlorobenzoic acid: The manufacturing process of Bumetanide starts with the sulfonylchlorination of 4-chlorobenzoic acid with chlorosulfonic acid to form 4-chloro-3-chlorosulfonylbenzoic acid, which is then nitrated with nitric acid to form an intermediate. The intermediate is treated with ammonia to produce another intermediate, which is then reacted with sodium phenolate to form 5-amino-sulfonyl-3-nitro-5-phenoxybenzoid acid. The nitro group in this compound is reduced by hydrogen using a palladium-on carbon catalyst to give 3-amino-5-aminosulfonyl-5-phenoxybenzoic acid. Finally, this compound is reacted with butyl alcohol in the presence of sulfuric acid to produce Bumetanide.

Bumetanide, commercially known as Bumex, is a crystalline solid having the molecular formula C17H20N2O5S and a molecular weight of 364.4 g/mol. It has a melting point in the range of 230 - 231 °C. It has a water solubility of >20 mg/mL (in base). It has a log P value of 2.6. The value of its dissociation constant, pKa, is 3.83. It dissolves in acetone and alcohol, is soluble to some extent in methylene chloride, and is insoluble in water. Bumetanide is a sulfamyl diuretic that is used to treat nephrotic syndrome, liver and renal disease, and edema associated with congestive heart failure.

Product Details

Particulars Details
Product Name Bumetanide
Scope Manufacturing Process: Process Flow, Material Flow, Material Balance

Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation

Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital

Variable Cost: Raw Material, Utilities, Other Variable Costs

Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs

Financing Costs: Interest on Working Capital, Interest on Loans

Other Costs: Depreciation Charges, General Sales and Admin Cost
Currency US$ (Data can also be provided in the local currency)
Pricing and Purchase Options Basic: US$ 2499
Premium: US$ 3499
Enterprise: US$ 4799
Customization Scope The report can be customized as per the requirement of the customer
Post-Sale Analysts Report 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable
Delivery Format PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request)

How does our Bumetanide Production Cost Report Provide Exhaustive Data and Extensive Insights?

At Procurement Resource, we not only focus on optimizing the should cost of production for Bumetanide but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.

We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Bumetanide market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.

Key Questions Answered in This Report

  • What are the key requirements for setting up a Bumetanide manufacturing plant?
  • How is Bumetanide manufactured?
  • What is the process flow involved in producing Bumetanide?
  • What are the raw material requirements and costs for producing Bumetanide?
  • What is the total size of land required for setting up a Bumetanide manufacturing plant?
  • What are the construction requirements for setting up a Bumetanide manufacturing plant?
  • What are the machinery requirements for producing Bumetanide?
  • What are the utility requirements and costs for producing Bumetanide?
  • What are the manpower requirements for producing Bumetanide?
  • What are the average salaries/wages of manpower working in a Bumetanide manufacturing plant?
  • What are the packaging requirements and associated costs for Bumetanide?
  • What are the transportation requirements and associated costs for Bumetanide?
  • What are the capital costs for setting up a Bumetanide manufacturing plant?
  • What are the operating costs for setting up a Bumetanide manufacturing plant?
  • What should be the price of Bumetanide?
  • What will be the income and expenditures for a Bumetanide manufacturing plant?

Need more help?

  • We can tailor the report as per your unique requirements such as desired capacity, future expansion plans, product specifications, mode of financing, plant location, etc.
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  • Speak to our highly skilled team of analysts for insights on the recent trends and innovations, industry best practices, key success and risk factors, product pricing, margins, return on investment, industry standards and regulations, etc.
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