Cabazitaxel Production Cost Reports
Healthcare
The report provides a detailed analysis essential for establishing a Cabazitaxel manufacturing plant. It encompasses all critical aspects necessary for Cabazitaxel production, including the cost of Cabazitaxel production, Cabazitaxel plant cost, Cabazitaxel production costs, and the overall Cabazitaxel manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Cabazitaxel production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Cabazitaxel is a chemotherapy drug used to treat advanced prostate cancer that has spread to other parts of the body and no longer responds to hormone therapy or docetaxel chemotherapy. It is given in combination with a steroid medication called prednisone. It is a second-generation semisynthetic microtubule inhibitor that stabilizes microtubules. It also acts as an antineoplastic medication causing tumor death. It is synthesized from 10-deacetylbaccatin III, a substance that has been separated from yew trees.
The procurement of Cabazitaxel is influenced by its application in the pharmaceutical and medical industries as a chemotherapy drug used to treat advanced prostate cancer. The demand for Cabazitaxel is also increasing due to the rising cases of prostate cancer. Prostate cancer is the most frequent malignancy in males, which also happens to be the second largest cause of mortality from cancer in men, thus promoting the demand for drugs like Cabazitaxel.
It is given in combination with a steroid medication called Prednisone. It can also be utilized in combination with Prednisolone. Clinical trial results also showed that it is useful in increasing the overall survival rate in patients with prostate cancer, which enhances its demand. Overall, the industrial Cabazitaxel procurement is influenced by its application in the pharmaceutical and medical industries, combination therapy, clinical trial success rate, efficacy, rising cases of prostate cancer, healthcare awareness, technological advancements, cost and pricing, and regulatory approvals.
Raw Material for Cabazitaxel Production
According to the Cabazitaxel manufacturing plant project report, the key raw material used in the production of Cabazitaxel includes 10-deacetylbaccatin III.
Manufacturing Process of Cabazitaxel
The extensive Cabazitaxel production cost report consists of the following major industrial manufacturing process:
- Production from 10-deacetylbaccatin III: The manufacturing process of Cabazitaxel starts with the hydroxy protection of 10-deacetylbaccatin III with 2,2,2-trichloroethyl chloroformate to form the 7,10-di-Troc compound, which is subsequently nucleophilically substituted with ((chloromethoxy)methyl)benzene by N,N-diisopropylethylamine (DIPEA) promoted nucleophilic substitution, resulting in O-BOM (benzyloxymethyl). After being treated with Zn power, the compound experiences the elimination of Troc, resulting in an intermediate. The intermediate is subjected to alkaline conditions with methyl iodide to form an ether intermediate. O-deprotection in acid then produces the alcohol intermediate. Subsequently, an ester compound is produced by condensation of the alcohol intermediate with carboxylic acid compound and ring-opening in acid to produce Cabazitaxel.
Cabazitaxel, commercially known as Jevtana, is a yellow to brown-yellow viscous solution, having the molecular formula C45H57NO14 and a molecular weight of 835.9 g/mol. It has a melting point of around 170 °C. It has a water solubility of 0.00413 mg/mL. Its log P value is 3.69, and the value of its dissociation constant, pKa, is 11.96. Cabazitaxel is derived from 10-deacetylbaccatin III, a substance that has been separated from yew trees. It is a second-generation semisynthetic microtubule inhibitor that functions in stabilizing microtubules and causes tumor cell death.
Product Details
| Particulars | Details |
|---|---|
| Product Name | Cabazitaxel |
| Scope | Manufacturing Process: Process Flow, Material Flow, Material Balance Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital Variable Cost: Raw Material, Utilities, Other Variable Costs Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs Financing Costs: Interest on Working Capital, Interest on Loans Other Costs: Depreciation Charges, General Sales and Admin Cost |
| Currency | US$ (Data can also be provided in the local currency) |
| Pricing and Purchase Options | Basic: US$ 2499 Premium: US$ 3499 Enterprise: US$ 4799 |
| Customization Scope | The report can be customized as per the requirement of the customer |
| Post-Sale Analysts Report | 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable |
| Delivery Format | PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request) |
How does our Cabazitaxel Production Cost Report Provide Exhaustive Data and Extensive Insights?
At Procurement Resource, we not only focus on optimizing the should cost of production for Cabazitaxel but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.
We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Cabazitaxel market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.
Key Questions Answered in This Report
- What are the key requirements for setting up a Cabazitaxel manufacturing plant?
- How is Cabazitaxel manufactured?
- What is the process flow involved in producing Cabazitaxel?
- What are the raw material requirements and costs for producing Cabazitaxel?
- What is the total size of land required for setting up a Cabazitaxel manufacturing plant?
- What are the construction requirements for setting up a Cabazitaxel manufacturing plant?
- What are the machinery requirements for producing Cabazitaxel?
- What are the utility requirements and costs for producing Cabazitaxel?
- What are the manpower requirements for producing Cabazitaxel?
- What are the average salaries/wages of manpower working in a Cabazitaxel manufacturing plant?
- What are the packaging requirements and associated costs for Cabazitaxel?
- What are the transportation requirements and associated costs for Cabazitaxel?
- What are the capital costs for setting up a Cabazitaxel manufacturing plant?
- What are the operating costs for setting up a Cabazitaxel manufacturing plant?
- What should be the price of Cabazitaxel?
- What will be the income and expenditures for a Cabazitaxel manufacturing plant?
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