Carbamazepine Production Cost Reports

The report provides a detailed analysis essential for establishing a Carbamazepine manufacturing plant. It encompasses all critical aspects necessary for Carbamazepine production, including the cost of Carbamazepine production, Carbamazepine plant cost, Carbamazepine production costs, and the overall Carbamazepine manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Carbamazepine production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Carbamazepine is a non-narcotic analgesic drug with anticonvulsant and analgesic properties. It is widely used as an oral drug for the treatment of epilepsy, particularly for partial seizures and generalized tonic-clonic seizures. It also finds its applications as a medication in the treatment and management of bipolar disorder during manic episodes. It is also utilized as an anticonvulsant for the treatment of psychomotor or focal seizures by reducing abnormal electrical activity in the brain. It is often used as a drug in the treatment of trigeminal neuralgia and other neuropathic pain syndromes.

The market for Carbamazepine is predominantly driven by its demand as an FDA-approved anticonvulsant drug and an analgesic drug used to control seizures. Its application as an antimanic drug in the treatment of bipolar disorder and epilepsy further enhances its demand in the medical and pharmaceutical industries. Its utilization as an effective medication in the treatment and management of the symptoms associated with trigeminal neuralgia also contributes to its demand in the medical and pharmaceutical industries. As a pharmaceutical compound, Carbamazepine must meet stringent regulatory standards set by bodies such as the EMA (European Medicines Agency or FDA (U.S. Food and Drug Administration). Thus, compliance with these regulatory standards associated with its high-quality production and usage in medicine directly affects the availability and industrial Carbamazepine procurement. Carbamazepine must be stored in conditions that do not compromise its chemical stability. Therefore, efficient distribution networks and proper storage solutions serve as crucial factors in shaping procurement strategies.

Raw Material for Carbamazepine Production

According to the Carbamazepine manufacturing plant project report, the major raw materials for Carbamazepine production include 5H-dibenz[b,f]azepine (Dibenzazepine) or Iminostilbene and Phosgene and Ammonia.

Manufacturing Process of Carbamazepine

The extensive Carbamazepine production cost report consists of the following industrial manufacturing process:

• Production from 4-methylhexanone-2: This method of production involves the synthesis of Carbamazepine through the process of phosgenation and dehydrochlorination. The process begins with the reaction of 5H-dibenz[b,f]azepine and phosgene to give 5-chlorcarboxy-5H-dibenz-[b,f]azepine. Further, the obtained compound is reacted with ammonia, which results in the formation of 5H-dibenz[b,f]azepine-5-carboxamide or carbamazepine as the final product.

Carbamazepine is a tricyclic compound and a dibenzoazepine that serves as an antimanic drug. It is also known as Tegretol. It is regarded as the first anticonvulsant used for the treatment of individuals with bipolar disorder. The molecular formula of the compound is C15H12N2O, and its molecular weight is 236.27 g/mol. It appears as a white to off-white powder and is not soluble in water. The boiling point of the compound is 411°C, and its melting point is around 190.2 °C. The value of LogP is 2.77, and its pka value is 13.9. The compound is also considered to cause developmental toxicity.