Cefonicid Production Cost Reports

The report provides a detailed analysis essential for establishing a Cefonicid manufacturing plant. It encompasses all critical aspects necessary for Cefonicid production, including the cost of Cefonicid production, Cefonicid plant cost, Cefonicid production costs, and the overall Cefonicid manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Cefonicid production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Cefonicid is a medication used to treat various bacterial infections. It is used to treat infections such as soft tissue and bone infections, lower respiratory tract infections, and urinary tract infections. It is a member of class of drugs called second-generation cephalosporin antibiotics. Its ability to inhibit cell wall formation is what gives it its bactericidal activity. By attaching itself to certain penicillin-binding proteins (PBPs) present inside the bacterial cell wall, it suppresses the third and last stage of bacterial cell wall synthesis.

The procurement of Cefonicid is influenced by its application in the pharmaceutical and medical industries as an antibiotic given for the treatment of various bacterial infections such as soft tissue and bone infections, lower respiratory tract infections, and urinary tract infections. The demand for Cefonicid is also increasing due to the rising cases of bacterial infections. The pharmaceutical industry's ongoing research and development efforts have resulted in the development of novel and improved antibiotics, such as Cefonicid, with improved safety and effectiveness profiles, which increases its demand. The increasing bacterial resistance has been reported towards the first generation cephalosporins; therefore, second-generation drugs such as Cefonicid are recommended to have better activity against pathogens.

Availability of health care services and health organizations especially in the developing world has enhanced supply of antibiotics thus resulting in high demand Cefonicid. Overall, the industrial Cefonicid procurement is influenced by its application in the pharmaceutical and medical industries, its wide range of applications, its utilization with other antibiotics, fewer side effects, better tolerability, clinical studies, research and development, rising cases of bacterial infections, increasing healthcare awareness, and regulatory approvals.

Raw Material for Cefonicid Production

According to the Cefonicid manufacturing plant project report, the key raw material used in the production of Cefonicid includes 7-aminocephalosporanic acid.

Manufacturing Process of Cefonicid

The extensive Cefonicid production cost report consists of the following major industrial manufacturing process:

• Production from 7-aminocephalosporanic acid: The manufacturing process of Cefonicid starts with the acylation of the starting compound with o-protected mandeloyl chloride to form an intermediate. The 3′-acetoxy group of the intermediate is subjected to displacement with sulfomethyl tetrazole thiol to form another intermediate. Finally, the o-protective group is removed to produce Cefonicid.

Cefonicid, commercially known as Sintocef, appears as a white to off-white powder, having the molecular formula C18H18N6O8S3 and a molecular weight of 542.6 g/mol. It is soluble in water with a solubility of 0.895 mg/mL. The value of its log P is -0.71. It has a density of around 1.92 g/cm³. The value of its dissociation constant, pKa, is -1.3. It is a second-generation cephalosporin antibiotic. Its inhibition of cell wall formation is what gives it its bactericidal activity. It is used to treat soft tissue and bone infections, lower respiratory tract infections, and urinary tract infections.