Clomiphene Production Cost Reports

Healthcare

The report provides a detailed analysis essential for establishing a Clomiphene manufacturing plant. It encompasses all critical aspects necessary for Clomiphene production, including the cost of Clomiphene production, Clomiphene plant cost, Clomiphene production costs, and the overall Clomiphene manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Clomiphene production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Clomiphene, commonly referred to as Clomifene is an FDA approved drug with components of an estrogen agonist and an estrogen antagonist that is commonly used to treat infertility in women. It is useful for women who have a condition of irregular or no menstruation that can be worsened by diseases like PCOS (polycystic ovarian syndrome). It counteracts the actions of estrogen which causes the secretion of more hormones from the brain that in turns stimulates the ovaries to release a fully developed egg. In addition, by increasing the secretion of luteinizing hormone and follicle-stimulating hormone that leads to the increase in testosterone and spermatogenesis, it is also used in the treatment of male infertility.

The market for Clomiphene is driven by its usage as an estrogen receptor modulator for the treatment of infertility in women, which significantly promotes its demand in the pharmaceutical and medical industries. The widespread occurrence of infertility in women is significantly increasing the demand for Clomiphene. Additionally, the rising cases of obesity and PCOS further contribute to its market growth. The drug’s utility extends to off-label uses, such as secondary hypogonadism, performance enhancement for healthy athletes, and primary short-lasting unilateral neuralgiform headache attacks (SUNCT), amplifying its market appeal. Overall, industrial Clomiphene procurement is influenced by its usage in the pharmaceutical and medical industries, rising cases of infertility, PCOS, and obesity, off-label uses, increasing healthcare awareness, and regulatory approvals.

Raw Material for Clomiphene Production

According to the Clomiphene manufacturing plant project report, the key raw material used in the production of Clomiphene includes 4-hydroxybenzophenone.

Manufacturing Process of Clomiphene

The extensive Clomiphene production cost report consists of the following major industrial manufacturing process:

  1. Production from 4-hydroxybenzophenone: The manufacturing process of Clomiphene starts with the reaction of 4-hydroxybenzophenone with 2-diethylaminoethylchloride in the presence of an alkali to form 4-(2-diethylaminoethoxy)benzophenone. The resulting compound is treated with benzylmagnesium chloride in a Grignard reaction to give the corresponding carbinol. The carbinol is subjected to dehydration with hydrogen chloride to give 2-[p-(1,2-diphenylvinyl) phenoxy]triethylamine. Finally, the vinylic hydrogen atom of the compound is replaced with a chlorine atom using N-chlorosuccinimide to produce Clomiphene.

Clomiphene, commercially known as Clomid, is a white to pale-yellow powder having the molecular formula C26H28ClNO and a molecular weight of 406.0 g/mol. It has a melting point in the range of 116.5-118 °C. It is slightly soluble in water with an estimated water solubility of 0.000414 mg/mL. It is also soluble in ethanol and chloroform but dissolves better in methanol. Moreover, it is almost insoluble in diethyl ether. It has a log P value of around 7.2. The value of its dissociation constant, pKa, is 9.31. It becomes unstable when exposed to air and light. It is hygroscopic. It is an estrogen receptor modulator (agonist/antagonist depending on the target tissue). It is a triphenyl ethylene stilbene derivative used to treat infertility in women and PCOS.

Product Details

Particulars Details
Product Name Clomiphene
Scope Manufacturing Process: Process Flow, Material Flow, Material Balance

Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation

Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital

Variable Cost: Raw Material, Utilities, Other Variable Costs

Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs

Financing Costs: Interest on Working Capital, Interest on Loans

Other Costs: Depreciation Charges, General Sales and Admin Cost
Currency US$ (Data can also be provided in the local currency)
Pricing and Purchase Options Basic: US$ 2499
Premium: US$ 3499
Enterprise: US$ 4799
Customization Scope The report can be customized as per the requirement of the customer
Post-Sale Analysts Report 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable
Delivery Format PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request)

How does our Clomiphene Production Cost Report Provide Exhaustive Data and Extensive Insights?

At Procurement Resource, we not only focus on optimizing the should cost of production for Clomiphene but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.

We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Clomiphene market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.

Key Questions Answered in This Report

  • What are the key requirements for setting up a Clomiphene manufacturing plant?
  • How is Clomiphene manufactured?
  • What is the process flow involved in producing Clomiphene?
  • What are the raw material requirements and costs for producing Clomiphene?
  • What is the total size of land required for setting up a Clomiphene manufacturing plant?
  • What are the construction requirements for setting up a Clomiphene manufacturing plant?
  • What are the machinery requirements for producing Clomiphene?
  • What are the utility requirements and costs for producing Clomiphene?
  • What are the manpower requirements for producing Clomiphene?
  • What are the average salaries/wages of manpower working in a Clomiphene manufacturing plant?
  • What are the packaging requirements and associated costs for Clomiphene?
  • What are the transportation requirements and associated costs for Clomiphene?
  • What are the capital costs for setting up a Clomiphene manufacturing plant?
  • What are the operating costs for setting up a Clomiphene manufacturing plant?
  • What should be the price of Clomiphene?
  • What will be the income and expenditures for a Clomiphene manufacturing plant?

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