Clopidogrel Production Cost Reports

Healthcare

The report provides a detailed analysis essential for establishing a Clopidogrel manufacturing plant. It encompasses all critical aspects necessary for Clopidogrel production, including the cost of Clopidogrel production, Clopidogrel plant cost, Clopidogrel production costs, and the overall Clopidogrel manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Clopidogrel production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Clopidogrel stops blood clots formation and can reduce the chances of having a heart attack or stroke. Its mode of action is to block platelet receptors, thereby preventing them from being aggregated. It can benefit those who have non-ST elevation acute coronary syndrome (ACS) or ST-elevation myocardial infarction. For patients who have recently had TIAs, it is a good option for preventing strokes. It helps in the prevention of blood clotting and does vasodilation, thus treating peripheral vascular diseases. Clopidogrel with aspirin helps to manage Acute Coronary Syndromes (ACS) and improve blood flow in the heart vessels following interventional procedures of some coronary surgery.

The Clopidogrel market is mainly driven by increased demand for antiplatelet medication because of the need to prevent heart attacks and strokes. It is used in the treatment of various types of myocardial infarction and may be beneficial for patients who have experienced a transient ischemic attack. It is also used to treat peripheral vascular disease and keep the blood flow. It is used along with aspirin to treat acute coronary syndromes following cardiac procedures and has a large market in post-operative medication. Due to cheap and readily available medicines, it is very useful in healthcare. So, its demand as an antiplatelet medication and its easy accessibility, along with its production prices, market prices, and logistics, directly influence industrial Clopidogrel procurement in the market across the globe.

Raw Material for Clopidogrel Production

According to the Clopidogrel manufacturing plant project report, the key raw materials used in the production of Clopidogrel include 2-chlorobenzyl cyanide- Bromine-( 4,5,6,7-tetrahydrothieno[3,2-c] pyridine hydrochloride)-KOH-Isopropyl Alcohol-Sulphuric Acid-Methanol-Hydrochloric Acid-Acetone- Camphor sulfonic acid-Sodium Bicarbonate.

Manufacturing Process of Clopidogrel

The extensive Clopidogrel production cost report consists of the following major industrial manufacturing process:

  • From 2-Chlorobenzyl cyanide, Bromine, 4,5,6,7-tetrahydrothieno[3,2-c] pyridine hydrochloride, KOH, isopropyl alcohol, Sulphuric Acid, methanol, Hydrochloric Acid, acetone, camphor sulfonic acid, and sodium bicarbonate: Synthesis of Clopidogrel is a multistep process in the industrial arena. 2-chlorobenzyl cyanide is brominated by Bromine to produce an α-bromo-2-chlorobenzyl cyanide intermediate. The intermediate obtained then undergoes nucleophilic substitution and cyclization with 4,5,6,7-tetrahydrothieno[3,2-c] pyridine hydrochloride. It constitutes the core structure of thienopyridine with a 2-chlorophenyl group attached. This nitrile is hydrolyzed to a carboxylic acid. The acid is next esterified using a combination of sulphuric acid, methanol, hydrochloric acid, and acetone to yield methyl esters. Then, the ester is treated using hydrochloric acid (or camphor sulfonic acid) along with sodium bicarbonate to obtain Clopidogrel hydrogen sulfate.

Clopidogrel is a white to off-white powder. Its molecular formula is C16H16Cl NO2S, and it has a molecular weight of 321.82 g/mol. It has a density of around 1.317 g/cm³ and a boiling point of around 423.7 ± 45.0 °C. It is insoluble in water, having a neutral pH, but shows good solubility at a pH value of 1. It is easily soluble in methanol and insoluble in ethyl ether. It has 0 hydrogen bond donors and four rotatable bonds. Its topological polar surface area is 57.78 Ų, and its partition coefficient value is (LogP) 2.73. These physical and chemical properties are essential for its pharmacological applications.

Product Details

Particulars Details
Product Name Clopidogrel
Scope Manufacturing Process: Process Flow, Material Flow, Material Balance

Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation

Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital

Variable Cost: Raw Material, Utilities, Other Variable Costs

Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs

Financing Costs: Interest on Working Capital, Interest on Loans

Other Costs: Depreciation Charges, General Sales and Admin Cost
Currency US$ (Data can also be provided in the local currency)
Pricing and Purchase Options Basic: US$ 2499
Premium: US$ 3499
Enterprise: US$ 4799
Customization Scope The report can be customized as per the requirement of the customer
Post-Sale Analysts Report 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable
Delivery Format PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request)

How does our Clopidogrel Production Cost Report Provide Exhaustive Data and Extensive Insights?

At Procurement Resource, we not only focus on optimizing the should cost of production for Clopidogrel but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.

We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Clopidogrel market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.

Key Questions Answered in This Report

  • What are the key requirements for setting up a Clopidogrel manufacturing plant?
  • How is Clopidogrel manufactured?
  • What is the process flow involved in producing Clopidogrel?
  • What are the raw material requirements and costs for producing Clopidogrel?
  • What is the total size of land required for setting up a Clopidogrel manufacturing plant?
  • What are the construction requirements for setting up a Clopidogrel manufacturing plant?
  • What are the machinery requirements for producing Clopidogrel?
  • What are the utility requirements and costs for producing Clopidogrel?
  • What are the manpower requirements for producing Clopidogrel?
  • What are the average salaries/wages of manpower working in a Clopidogrel manufacturing plant?
  • What are the packaging requirements and associated costs for Clopidogrel?
  • What are the transportation requirements and associated costs for Clopidogrel?
  • What are the capital costs for setting up a Clopidogrel manufacturing plant?
  • What are the operating costs for setting up a Clopidogrel manufacturing plant?
  • What should be the price of Clopidogrel?
  • What will be the income and expenditures for a Clopidogrel manufacturing plant?

Need more help?

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