Crisaborole Production Cost Reports
Healthcare
The report provides a detailed analysis essential for establishing a Crisaborole manufacturing plant. It encompasses all critical aspects necessary for Crisaborole production, including the cost of Crisaborole production, Crisaborole plant cost, Crisaborole production costs, and the overall Crisaborole manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Crisaborole production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Crisaborole is an FDA-approved drug that is widely known for its anti-inflammatory properties. It is widely used for the treatment of mild to moderate atopic dermatitis (AD) in patients two years and older. Moreover, it also finds its application as a topical ointment to treat and reduce inflammation and itching in both adults and children. Additionally, it is also used as a non-steroidal anti-inflammatory drug (NSAID) for alleviating symptoms of various skin inflammation.
The demand for Crisaborole is predominantly driven due to its key role as a steroid-free topical treatment for atopic dermatitis (AD) or eczema in adults and pediatric patients, which significantly boosts its demand in the pharmaceutical industry. Moreover, its usage for the treatment of various inflammatory skin conditions, such as redness, rashes, and itchiness, further accentuates its demand in the medical and healthcare industries. Additionally, factors, including the availability of raw materials (4-Hydroxy-3-bromobenzaldehyde, etc.), pricing, its application as topical treatment, compliance with healthcare regulations, scientific advancements, and quality standards, greatly influence industrial Crisaborole procurement globally.
Raw Material for Crisaborole Production
According to the Crisaborole manufacturing plant project report, the major raw material for Crisaborole production includes 4-Hydroxy-3-bromobenzaldehyde.
Manufacturing Process of Crisaborole
The extensive Crisaborole production cost report consists of the following industrial manufacturing process:
- Production via Chemical Synthesis: This method of production is initiated by subjecting bromobenzaldehyde (4-Hydroxy-3-bromobenzaldehyde) to warm ethylene glycol in the presence of catalytic p-toluenesulfonic acid to form the corresponding acetal. Further, the obtained compound (acetal) undergoes nucleophilic aromatic substitution on reaction with fluorobenzonitrile to obtain diaryl ether. Then, the obtained diaryl ether undergoes a reduction in the presence of sodium borohydride, followed by protection with THP to form a bromobenzene intermediate. Then, the obtained product is subjected to lithium-halogen exchange, followed by a reaction with triisopropyl borate and acidification, which results in the formation of crisaborole as the final product.
Crisaborole belongs to the family of benzoxaboroles. The molecular formula of the compound is C14H10BN03, and its molar mass is 251.05 g/mol. The compound is an aromatic ether that serves as a non-steroidal anti-inflammatory drug. Moreover, the IUPAC name of the compound is 4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile. The boiling point of the compound is 425.9°C, and its melting point is >130°C. The density of the compound is 1.33g/cm3, and it is generally stored at room temperature. Additionally, the compound is hygroscopic, white to beige powder that is slightly soluble in DMSO and Menthol. This drug is sold under the trade name EUCRISA and is only meant for topical use.
Product Details
| Particulars | Details |
|---|---|
| Product Name | Crisaborole |
| Scope | Manufacturing Process: Process Flow, Material Flow, Material Balance Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital Variable Cost: Raw Material, Utilities, Other Variable Costs Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs Financing Costs: Interest on Working Capital, Interest on Loans Other Costs: Depreciation Charges, General Sales and Admin Cost |
| Currency | US$ (Data can also be provided in the local currency) |
| Pricing and Purchase Options | Basic: US$ 2499 Premium: US$ 3499 Enterprise: US$ 4799 |
| Customization Scope | The report can be customized as per the requirement of the customer |
| Post-Sale Analysts Report | 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable |
| Delivery Format | PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request) |
How does our Crisaborole Production Cost Report Provide Exhaustive Data and Extensive Insights?
At Procurement Resource, we not only focus on optimizing the should cost of production for Crisaborole but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.
We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Crisaborole market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.
Key Questions Answered in This Report
- What are the key requirements for setting up a Crisaborole manufacturing plant?
- How is Crisaborole manufactured?
- What is the process flow involved in producing Crisaborole?
- What are the raw material requirements and costs for producing Crisaborole?
- What is the total size of land required for setting up a Crisaborole manufacturing plant?
- What are the construction requirements for setting up a Crisaborole manufacturing plant?
- What are the machinery requirements for producing Crisaborole?
- What are the utility requirements and costs for producing Crisaborole?
- What are the manpower requirements for producing Crisaborole?
- What are the average salaries/wages of manpower working in a Crisaborole manufacturing plant?
- What are the packaging requirements and associated costs for Crisaborole?
- What are the transportation requirements and associated costs for Crisaborole?
- What are the capital costs for setting up a Crisaborole manufacturing plant?
- What are the operating costs for setting up a Crisaborole manufacturing plant?
- What should be the price of Crisaborole?
- What will be the income and expenditures for a Crisaborole manufacturing plant?
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