Dantrolene Production Cost Reports

Healthcare

The report provides a detailed analysis essential for establishing a Dantrolene manufacturing plant. It encompasses all critical aspects necessary for Dantrolene production, including the cost of Dantrolene production, Dantrolene plant cost, Dantrolene production costs, and the overall Dantrolene manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Dantrolene production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Dantrolene is an FDA-approved medication used in both adults and children for the management of malignant hyperthermia, an extremely uncommon but potentially fatal condition brought on by general anesthesia. Additionally, Dantrolene has been licensed by the FDA for use in other conditions such as multiple sclerosis, cerebral palsy, spinal cord injury, stroke, and disorders involving muscle spasticity. Dantrolene is also used to treat overdoses of 2,4-dinitrophenol, which is a “fat burner” drug that is illegal and inhibits ATP production, resulting in hyperthermia.

The market for Dantrolene is driven by its usage as a hydantoin derivative and skeletal muscle relaxant for the treatment of malignant hyperthermia, which significantly promotes its demand in the pharmaceutical and medical industries. The widespread occurrence of malignant hyperthermia is significantly increasing the demand for Dantrolene. The aging population is more susceptible to muscle stiffness and frequent muscle spasms, which accelerates the demand for muscle relaxants like Dantrolene.

The drug’s utility extends to off-label uses, such as multiple sclerosis, cerebral palsy, spinal cord injury, and muscle spasticity, which further promotes its demand in the pharmaceutical industry and amplifies its market presence. Overall, industrial Dantrolene procurement is influenced by its usage in the pharmaceutical and medical industries, rising cases of malignant hyperthermia, off-label uses, increasing healthcare awareness, technological advancements, and regulatory approvals.

Raw Material for Dantrolene Production

According to the Dantrolene manufacturing plant project report, the key raw material used in the production of Dantrolene includes 4-nitrophenyldiazonium chloride.

Manufacturing Process of Dantrolene

The extensive Dantrolene production cost report consists of the following major industrial manufacturing process:

  • Production from 4-nitrophenyldiazonium chloride: The manufacturing process of Dantrolene starts with the reaction of the starting compound with furfurol to form 5-(4-nitrophenyl)-2-furancarboxaldehyde. The compound further reacts with 1-aminohydantoin, to produce the corresponding hydrazone, Dantrolene.

Dantrolene, commercially known as Dantrium, Revonto, or Ryanodex, is an odorless and tasteless substance having the molecular formula C14H10N4O5 and a molecular weight of 314.25 g/mol. It has a melting point in the range of 279-280 °C. It has a low (146 mg/L) water solubility. It has an estimated water solubility of 0.0805 mg/mL. It is easily soluble in alkaline solution. It has a log P value of 1.70. The value of its dissociation constant, pKa, is 8.23. It remains stable in light, air, and heat but hydrolyzes in water. It decomposes between the range of 225 & 230 °C. It is rapidly observed after oral administration. Although Dantrolene is a derivative of hydantoin chemically, it lacks the antiepileptic properties of phenytoin and other hydantoin derivatives. It is a skeletal muscle relaxant used to treat malignant hyperthermia.

Product Details

Particulars Details
Product Name Dantrolene
Scope Manufacturing Process: Process Flow, Material Flow, Material Balance

Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation

Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital

Variable Cost: Raw Material, Utilities, Other Variable Costs

Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs

Financing Costs: Interest on Working Capital, Interest on Loans

Other Costs: Depreciation Charges, General Sales and Admin Cost
Currency US$ (Data can also be provided in the local currency)
Pricing and Purchase Options Basic: US$ 2499
Premium: US$ 3499
Enterprise: US$ 4799
Customization Scope The report can be customized as per the requirement of the customer
Post-Sale Analysts Report 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable
Delivery Format PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request)

How does our Dantrolene Production Cost Report Provide Exhaustive Data and Extensive Insights?

At Procurement Resource, we not only focus on optimizing the should cost of production for Dantrolene but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.

We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Dantrolene market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.

Key Questions Answered in This Report

  • What are the key requirements for setting up a Dantrolene manufacturing plant?
  • How is Dantrolene manufactured?
  • What is the process flow involved in producing Dantrolene?
  • What are the raw material requirements and costs for producing Dantrolene?
  • What is the total size of land required for setting up a Dantrolene manufacturing plant?
  • What are the construction requirements for setting up a Dantrolene manufacturing plant?
  • What are the machinery requirements for producing Dantrolene?
  • What are the utility requirements and costs for producing Dantrolene?
  • What are the manpower requirements for producing Dantrolene?
  • What are the average salaries/wages of manpower working in a Dantrolene manufacturing plant?
  • What are the packaging requirements and associated costs for Dantrolene?
  • What are the transportation requirements and associated costs for Dantrolene?
  • What are the capital costs for setting up a Dantrolene manufacturing plant?
  • What are the operating costs for setting up a Dantrolene manufacturing plant?
  • What should be the price of Dantrolene?
  • What will be the income and expenditures for a Dantrolene manufacturing plant?

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