Didanosine Production Cost Reports

Healthcare

The report provides a detailed analysis essential for establishing a Didanosine manufacturing plant. It encompasses all critical aspects necessary for Didanosine production, including the cost of Didanosine production, Didanosine plant cost, Didanosine production costs, and the overall Didanosine manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Didanosine production plant.

These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Didanosine belongs to the group of anti-viral drugs and serves for the treatment of HIV (Human Immunodeficiency Virus) disease. It is part of a group of drugs known as reverse transcriptase inhibitors, which prevent a virus called reverse transcriptase that HIV requires to reproduce in the body.

It slows down this enzyme to decrease the virus development in the organism and help to keep the immune system functioning. It is employed together with other antiretroviral drugs as part of a complete HIV treatment regimen and this combination therapy has proved to be more effective in preventing the virus from advancing to AIDS.

The procurement of Didanosine is influenced by its application in the pharmaceutical and medical industries as an antiviral medication used to treat HIV-1 infection. The widespread occurrence of viral infections is significantly increasing the demand for Didanosine. Didanosine has been evidenced to enhance the management of HIV infection with sustained declines in plasma HIV RNA levels and CD4+ cell count increase, which increases the demand.

It is taken along with at least one other antiretroviral substance to increase its therapeutic effect. Its enduring involvement in the treatment management programmes is partly attributed to its ability to be used in compound drug administration, thus enhancing its market appeal. Didanosine has several dosages that can be followed flexibly depending on the needs of the patient. The drug can be administered once or twice daily.

The dosing options have been stretched by the fact that there are both immediate-release and extended-release forms of the drug, and this is what boosts its demand. Overall, industrial Didanosine procurement is influenced by its application in the pharmaceutical and medical industries as an antiviral medication, rising cases of HIV-1 infections, combination therapy, better efficacy, fewer side effects, better tolerability, flexible dosing schedules, and regulatory approvals.

Raw Material for Didanosine Production

According to the Didanosine manufacturing plant project report, the key raw material used in the production of Didanosine includes 2′-deoxyinosine.

Manufacturing Process of Didanosine

The extensive Didanosine production cost report consists of the following major industrial manufacturing process:

  • Production from 2′-deoxyinosine: The manufacturing process of Didanosine starts with the protection of the 5′ hydroxyl group of 2’-deoxyinosine through a benzoylation reaction in the presence of pyridine to form 5′-O-benzoyl-2′-deoxyinosine. This compound is reacted with 1,1'-Thiocarbonyldiimidazole , resulting in the addition of the thiocarbonylimidazole group at 3′ position to give an intermediate. The intermediate undergoes deoxygenation at 3′ position to form 5′-O-benzoyl-2′,3′-dideoxyinosine. Finally, the 5′ hydroxyl group of the compound is deprotected by treating it with anhydrous methanol and ammonia to produce Didanosine.

Didanosine, commercially known as Videx, is a white and hygroscopic crystalline powder having the molecular formula C10H12N4O3 and a molecular weight of 236.23 g/mol. It has a melting point in the range of 160-163 °C. It has a water solubility of 15.8 mg/mL. It has an estimated water solubility of 6.58 mg/mL. The value of its dissociation constant, pKa, is 9.13. It is a nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV-1 infection.

Product Details

Particulars Details
Product Name Didanosine
Scope Manufacturing Process: Process Flow, Material Flow, Material Balance

Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation

Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital

Variable Cost: Raw Material, Utilities, Other Variable Costs

Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs

Financing Costs: Interest on Working Capital, Interest on Loans

Other Costs: Depreciation Charges, General Sales and Admin Cost
Currency US$ (Data can also be provided in the local currency)
Pricing and Purchase Options Basic: US$ 2499
Premium: US$ 3499
Enterprise: US$ 4799
Customization Scope The report can be customized as per the requirement of the customer
Post-Sale Analysts Report 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable
Delivery Format PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request)

How does our Didanosine Production Cost Report Provide Exhaustive Data and Extensive Insights?

At Procurement Resource, we not only focus on optimizing the should cost of production for Didanosine but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.

We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Didanosine market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.

Key Questions Answered in This Report

  • What are the key requirements for setting up a Didanosine manufacturing plant?
  • How is Didanosine manufactured?
  • What is the process flow involved in producing Didanosine?
  • What are the raw material requirements and costs for producing Didanosine?
  • What is the total size of land required for setting up a Didanosine manufacturing plant?
  • What are the construction requirements for setting up a Didanosine manufacturing plant?
  • What are the machinery requirements for producing Didanosine?
  • What are the utility requirements and costs for producing Didanosine?
  • What are the manpower requirements for producing Didanosine?
  • What are the average salaries/wages of manpower working in a Didanosine manufacturing plant?
  • What are the packaging requirements and associated costs for Didanosine?
  • What are the transportation requirements and associated costs for Didanosine?
  • What are the capital costs for setting up a Didanosine manufacturing plant?
  • What are the operating costs for setting up a Didanosine manufacturing plant?
  • What should be the price of Didanosine?
  • What will be the income and expenditures for a Didanosine manufacturing plant?

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