Fenofibrate Production Cost Reports

The report provides a detailed analysis essential for establishing a Fenofibrate manufacturing plant. It encompasses all critical aspects necessary for Fenofibrate production, including the cost of Fenofibrate production, Fenofibrate plant cost, Fenofibrate production costs, and the overall Fenofibrate manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Fenofibrate production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Fenofibrate is a medication used to manage abnormal cholesterol levels in the body. It works by activating certain receptors that improve lipid metabolism, lower LDL-C, and total cholesterol levels, and increase HDL-C levels. It is used in Hypercholesterolemia in adults for managing LDL-C and total cholesterol levels. It is used for treating elevated cholesterol and triglyceride levels because of Mixed Dyslipidemia. Fenofibrate is utilized for treating Severe Hypertriglyceridemia, reducing the risk of pancreatitis. It is found to slow down the development of diabetic retinopathy in patients having type 2 diabetes. It reduces the risk of amputation in diabetic patients having cardiovascular issues. It is effective in managing uric acid levels in individuals with gout.

The procurement of Fenofibrate globally is mainly driven by its effectiveness in managing cholesterol related problems. Its role in treating Hypercholesterolemia, mixed dyslipidemia, and severe hypertriglyceridemia drives its demand as a useful treatment option. It is clinically efficient in lowering LDL-C and triglyceride levels and increasing HDL-C, making it a popular product.

Fenofibrate can manage diabetic retinopathy and reduce amputation risks in diabetic patients, which further increases its demand. It is cost-effective and easily available, making it affordable and accessible mainly in developing regions. So, the developments in its demand in treating various cholesterol and diabetes-related problems, along with its affordability and accessibility significantly impact industrial Fenofibrate procurement in the market across the globe.

Raw Material for Fenofibrate Production

According to the Fenofibrate manufacturing plant project report, the key raw materials used in the production of Fenofibrate include 4-chlorobenzoic Acid-Phenol-Isopropyl Bromide-(2-bromo-2-methylpropanoate).

Manufacturing Process of Fenofibrate

The extensive Fenofibrate production cost report consists of the following major industrial manufacturing process:

• From 4-chlorobenzene Acid, Phenol, Isopropyl Bromide, and 2-bromo-2-methylpropanoate: The manufacturing process of Fenofibrate involves several steps. First, 4-chlorobenzoic acid is reacted with thionyl chloride forming 4-Chloro-4-Hydroxy Benzophenone. It is then treated with phenol, forming an intermediate compound. After that, this intermediate is reacted with isopropyl bromide, forming an isopropyl ester. This isopropyl ester is reacted with isopropyl 2-bromo-2-methylpropanoate, forming Fenofibrate. Finally, the Fenofibrate is separated and purified from the crude using chromatography.

Fenofibrate is a white-colored powder. Its IUPAC name is propan-2-yl 2-[4-(4-chlorobenzoyl) phenoxy]-2-methylpropanoate. Its molecular formula is C20H21ClO4, and it has a molecular weight of around 360.831 g/mol. Its melting point is 80.5°C. It has poor solubility in water. It is soluble in ethyl acetate, acetonitrile, and acetone. Its logP value is 5.6, which makes it lipophilic and soluble in fat. It is a chlorobenzophenone having a ketone linked to two phenyl groups. All these physical and chemical properties make it an important medication for managing cholesterol-related and several other problems.