Fenoprofen Calcium Production Cost Reports

The report provides a detailed analysis essential for establishing a Fenoprofen Calcium manufacturing plant. It encompasses all critical aspects necessary for Fenoprofen Calcium production, including the cost of Fenoprofen Calcium production, Fenoprofen Calcium plant cost, Fenoprofen Calcium production costs, and the overall Fenoprofen Calcium manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Fenoprofen Calcium production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Fenoprofen Calcium is an anti-inflammatory drug used to treat mild pain and inflammation. It is usually recommended to patients for mild to moderate pain from headaches, muscle aches, or pain that arises from an injury. Furthermore, it is also useful in conditions such as rheumatoid arthritis and osteoarthritis, helping reduce the pain and inflammation associated with the disorders. It functions as an anti-inflammatory, analgesic, and antipyretic medication.

The market for Fenoprofen Calcium is driven by various factors. It is used as an anti-inflammatory drug, an analgesic agent, and an antipyretic drug used to treat various ailments associated with pain which significantly promotes its growth in the pharmaceuticals and healthcare industries. The rising cases of osteoarthritis, rheumatoid arthritis, and injuries leading to pain and inflammation, are among many common conditions driving the demand for Fenoprofen Calcium.

The aging population is more susceptible to chronic pain and conditions such as rheumatoid arthritis, which accelerates the demand for anti-inflammatory drugs like Fenoprofen Calcium. The growing concerns over opioid addiction and side effects, causes a shift towards non-opioid pain relief options, boosting the market for non-steroidal anti-inflammatory drugs (NSAIDs) like Fenoprofen Calcium. Overall, industrial Fenoprofen Calcium procurement is influenced by its application in the pharmaceutical and medical industries, rising cases of chronic pain and conditions such as rheumatoid arthritis and osteoarthritis, the aging population, fewer side effects than opioid pain killers, increasing healthcare facilities and awareness, and regulatory approvals.

Raw Material for Fenoprofen Calcium Production

According to the Fenoprofen Calcium manufacturing plant project report, the key raw material used in the production of Fenoprofen Calcium includes 1-(3-hydroxyphenyl)ethan-1-one.

Manufacturing Process of Fenoprofen Calcium

The extensive Fenoprofen Calcium production cost report consists of the following major industrial manufacturing process:

• Production from 1-(3-hydroxyphenyl)ethan-1-one: The manufacturing process of Fenoprofen Calcium starts with the substitution of the starting compound with bromobenzene to form the ketone intermediate. The ketone undergoes reduction with NaBH4 to give the alcohol intermediate. The alcohol is subjected to chlorination with thionyl chloride to form another intermediate. The intermediate is further subjected to nucleophilic substitution reaction with NaCN to give the nitrile. The nitrile is treated with potassium carbonate in the presence of EtOH to form the final intermediate. Finally, the intermediate is treated with calcium carbonate in the presence of water to produce Fenoprofen Calcium.

Fenoprofen Calcium, commercially known as Fenortho or Nalfon, is the calcium salt of Fenoprofen. It is a white to off-white crystalline powder having the molecular formula C30H26CaO6 and a molecular weight of 522.6 g/mol. It is poorly soluble in water, with an estimated water solubility of 0.000128 mg/mL. It has a log P value in the range of 3.65 to 6.85. The value of its dissociation constant, pKa, is 3.96. It has a melting point of around 168 °C. It is a non-steroidal anti-inflammatory medication.