Fentanyl Production Cost Reports

The report provides a detailed analysis essential for establishing a Fentanyl manufacturing plant. It encompasses all critical aspects necessary for Fentanyl production, including the cost of Fentanyl production, Fentanyl plant cost, Fentanyl production costs, and the overall Fentanyl manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Fentanyl production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Fentanyl is a pain-relieving drug that has medicinal uses, mainly for pain management and anesthesia. It is a highly powerful analgesic and is said to be 20 to 40 times more potent than heroin and 100 times more potent than morphine. It works by stimulating μ-opioid receptors that are present in the central nervous system.

This stimulation alters the body’s response toward pain, providing sedation, pain relief, and respiratory depression. It works effectively in patients experiencing intense pain during surgery or people who have cancer. It is available in different formulations, such as lozenges, patches, and injectable solutions. However, it has a history of misuse, overdose, and illicit production, contributing to the recent health crisis.

The procurement of Fentanyl depends on various factors. It is a highly potent and effective analgesic, making it crucial for pain management. Its various formulations, such as injectable solutions, lozenges, patches, etc, make it flexible to different patient demands and clinical situations.

Fentanyl’s fast action and effectiveness in pain management further enhance its demand in the medical sector. Also, the increasing frequency of conditions that require strong pain relief contributes to the growing demand. Governing approvals and guidelines from health authorities ensure the legal use of Fentanyl and minimize the risks of misuse and overdose. The developments in its demand as an analgesic drug, along with its production prices, market prices, and logistics, directly influence industrial Fentanyl procurement globally.

Raw Material for Fentanyl Production

According to the Fentanyl manufacturing plant project report, the key raw materials used in the production of Fentanyl include (N-phenethyl-4-piperidinone(NPP))- propionyl chloride.

Manufacturing Process of Fentanyl

The extensive Fentanyl production cost report consists of the following major industrial manufacturing process:

• From N-phenethyl-4-piperidinon and propionyl chloride: The manufacturing process for Fentanyl has several steps (known as Siegfried method). At first, N-phenethyl-4-piperidinon is made to go through a condensation reaction that produces an intermediate compound 4-anilino-N-phenethyl-4-piperidine (ANPP).  After that, ANPP is reacted with propionyl chloride, and Fentanyl is obtained as the final product.

Fentanyl is a white crystalline powder and is slightly soluble in water but more soluble in alcohol.  It has a molecular formula of C22H28N2O and a molecular weight of 336.5 g/mol. It has a melting point of 83-84°C and a boiling point of 466°C. Its chemical structure is a piperidine derivative, specifically N-(1-(2-phenethyl)-4-piperidinyl)-N-phenyl-propanamide, contributing to its effectiveness as an analgesic.