Fexofenadine Production Cost Reports

The report provides a detailed analysis essential for establishing a Fexofenadine manufacturing plant. It encompasses all critical aspects necessary for Fexofenadine production, including the cost of Fexofenadine production, Fexofenadine plant cost, Fexofenadine production costs, and the overall Fexofenadine manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Fexofenadine production plant.

These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Fexofenadine is an antihistamine mainly used for treating allergic conditions.  It works by stopping the H1 histamine receptors, preventing the characteristic allergic reactions. It is used to treat seasonal allergic rhinitis that causes sneezing, runny nose, throat irritation, etc.

It manages itching and hives caused by chronic urticaria. It is preferred over traditional antihistamines as it doesn’t cause sedation and thus helps in maintaining alertness while treating the allergy. Fexofenadine is an important drug for treating allergies and reducing the discomfort caused by them. It has some side effects, but overall, it provides immediate relief for major allergies.

The Fexofenadine market is driven by various factors that mainly include its use as an antihistamine for treating allergies. Its use in treating allergic rhinitis and chronic urticaria contributes to its growing demand in the medical field. Its ability to prevent allergic reactions without causing sedation makes it a preferred choice over traditional antihistamines.

Its efficiency in offering quick relief from sneezing, runny nose, throat irritation, itching, and hives increases its demand among healthcare providers. The changes in its demand as an antiallergy drug, its preference over older antihistamine drugs, and its easy accessibility directly influence industrial Fexofenadine procurement in the market around the world.

Raw Material for Fexofenadine Production

According to the Fexofenadine manufacturing plant project report, the key raw materials used in the production of Fexofenadine include Phloretic Acid-Piperidine Derivative(4-PPBP)-(4-hydroxyphenylacetic Acid).

Manufacturing Process of Fexofenadine

The extensive Fexofenadine production cost report consists of the following major industrial manufacturing process:

• From Phloretic Acid, Piperidine Derivative(4-PPBP), and 4-hydroxyphenylacetic Acid: The manufacturing process of Fexofenadine consists of several steps. First, phloretic Acid is reacted with 4-PPBP forming an intermediate compound. This intermediate goes through a coupling reaction with 4-hydroxyphenylacetic Acid introducing the main functional group. After this, the product is hydrolyzed, forming the final Fexofenadine structure. The crude product is purified using crystallization or chromatography to obtain Fexofenadine.

Fexofenadine is a white to off-white powder. Its molecular formula is C32H39NO4 and it has a molecular weight of 538.1 g/mol. It is insoluble in water but soluble in DMSO and ethanol. Its logP value ranges from 2.94 to 5.02 making it hydrophobic. It has an acidic pKa value of 4.04 and a basic pKa value of 9.01. It has 10 rotatable bonds and 9 hydrogen bonds, donors, and acceptors. It has a polar surface area of 81 Ų. These notable physical and chemical properties contribute to its effectiveness as an antihistamine drug.