Fluconazole Production Cost Reports

The report provides a detailed analysis essential for establishing a Fluconazole manufacturing plant. It encompasses all critical aspects necessary for Fluconazole production, including the cost of Fluconazole production, Fluconazole plant cost, Fluconazole production costs, and the overall Fluconazole manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Fluconazole production plant.

These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Fluconazole is an antifungal medication that is used to treat several fungal infections. It works by stopping ergosterol production, which is important for fungal cell membranes, thus reducing fungal growth. It is used to treat candidiasis in women. It is used to cure infections like oral thrush and Esophageal candidiasis.

It is utilized in managing cryptococcal meningitis, mainly in HIV/AIDS patients. Fluconazole has been shown to be effective in systemic Candida infections in the bloodstream, kidneys, and joints. It is used for treating infections like histoplasmosis and blastomycosis. It is also used as a preventive drug in Individuals undergoing chemotherapy, Organ transplant, advanced HIV infections, and low neutrophil counts.

There are several key drivers that effect the market of Fluconazole being an important antifungal medication. It is effective in treating infections like candidiasis, cryptococcosis, histoplasmosis, and blastomycosis, which substantially improves its demand. It is efficient against Candida species and Cryptococcus neoformans, making it a preferred option in medical treatments.

It is available in affordable and accessible versions in many developing countries, which further contributes to its demand. It is also utilized for immunocompromised individuals, which further leads to its growing demand for antifungal usage. So, its effectiveness in treating numerous fungal infections, along with its affordability and accessibility in developing countries and its presence on the WHO's Essential Medicines list, directly affect industrial Fluconazole procurement in the market across the globe.

Raw Material for Fluconazole Production

According to the Fluconazole manufacturing plant project report, the key raw materials used in the production of Fluconazole include s-Triazole-Sodium Hydroxide-Bromine-Methylamine.

Manufacturing Process of Fluconazole

The extensive Fluconazole production cost report consists of the following major industrial manufacturing process:

• From s-Triazole, Sodium Hydroxide, Bromine, and Methylamine: The industrial manufacturing of Fluconazole involves several steps. First, s-triazole is reacted with a sodium hydroxide triazole ring. This triazole ring is modified by substitution reaction using a halogenation reagent like bromine. After that, methylamine is added to the compound to facilitate the defluoroamination process, forming Fluconazole. Finally, the product undergoes purification using recrystallization to separate the final Fluconazole product.

Fluconazole is a white to off-white solid powder. Its molecular formula is C13H12F2N6O and has a molecular weight of 306.27 g/mol. It has a density of 1.05 g/cm³. It is poorly soluble in water and shows better solubility in DMSO. It has a melting point of 138-140 °C and a boiling point of 579.8 °C. It is stored at temperatures ranging from 2 °C to 8 °C. It has a pKa value of 1.76 making it acidic. Its flash point is at 9 °C. It has a log P value of 0.4, making it lipophilic. All these properties make it an effective medication for fungal infections.