Gatifloxacin Production Cost Reports

The report provides a detailed analysis essential for establishing a Gatifloxacin manufacturing plant. It encompasses all critical aspects necessary for Gatifloxacin production, including the cost of Gatifloxacin production, Gatifloxacin plant cost, Gatifloxacin production costs, and the overall Gatifloxacin manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Gatifloxacin production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Gatifloxacin is an antibiotic used to treat various bacterial infections such as bronchitis, sinusitis, community-acquired pneumonia, and skin infections caused by S. pneumoniae, H. influenzae, S. aureus, M. pneumoniae, C. pneumoniae, L. pneumophila, S. pyogenes. Gatifloxacin belongs to the fourth generation of fluoroquinolones. It functions by preventing DNA gyrase and topoisomerase IV.

The procurement of Gatifloxacin is influenced by its application in the pharmaceutical and medical industries as an antibiotic used to treat various bacterial infections. The use of Gatifloxacin has been demanded more since cases of bacterial infections are rising. Compared to more established fluoroquinolones such as ciprofloxacin, it has a wider spectrum of activity, making it more efficacious against specific bacteria, particularly anaerobes and Gram-positive bacteria.

When it comes to common bacteria that cause skin, urinary tract, and respiratory infections, Gatifloxacin is an effective treatment. Gatifloxacin performs better than cefuroxime in treating acute bronchitis. Most of the patients respond favorably to Gatifloxacin, with only moderate side effects being noted. Also, it doesn't have any phototoxic effects, which is something that certain other antibiotics in its class may have. Since Gatifloxacin is usually given orally, a convenient once-daily dosing plan is made possible by its effectiveness. Overall, industrial Gatifloxacin procurement is influenced by its application in the pharmaceutical and medical industries as an antibiotic, rising cases of bacterial infections, fewer side effects, broad-spectrum, better tolerability, convenient dosing, enhanced efficacy, increased healthcare awareness, and regulatory approvals.

Raw Material for Gatifloxacin Production

According to the Gatifloxacin manufacturing plant project report, the key raw material used in the production of Gatifloxacin includes Moxifloxacin Difluoro Methoxy Ethyl Ester.

Manufacturing Process of Gatifloxacin

The extensive Gatifloxacin production cost report consists of the following major industrial manufacturing process:

• Production from Moxifloxacin Difluoro Methoxy Ethyl Ester: The manufacturing of Gatifloxacin starts with the reaction of Moxifloxacin Difluoro Methoxy Ethyl Ester with boron trifluoride diethyl etherate in the presence of methyl isobutyl ketone to form borondifluoride chelate. The chelate undergoes condensation with 2-methylpiperazine to give Gatifloxacin borondifluoride chelate. Finally, the chelate is subjected to hydrolysis by treatment with triethylamine to produce Gatifloxacin.

Gatifloxacin, commercially known as Zymar or Zymaxid, is a white to pale yellow crystalline powder having the molecular formula C19H22FN3O4 and a molecular weight of 375.4 g/mol. It has a melting point in the range of 182-185 °C. It has a water solubility of 60 mg/mL (at pH 4). It dissolves in dilute hydrochloric acid and dilute sodium hydroxide solutions and is soluble to some extent in chloroform and methanol. The value of its log P is 2.6. The value of its dissociation constant, pKa, is 8.74. As an antibiotic, Gatifloxacin belongs to the fourth generation of fluoroquinolones. It functions by preventing DNA gyrase and topoisomerase IV to treat various bacterial infections.