Irbesartan Production Cost Reports

The report provides a detailed analysis essential for establishing an Irbesartan manufacturing plant. It encompasses all critical aspects necessary for Irbesartan production, including the cost of Irbesartan production, Irbesartan plant cost, Irbesartan production costs, and the overall Irbesartan manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating an Irbesartan production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Irbesartan is a medication that is used to manage hypertension and diabetic nephropathy. It functions by preventing a hormone that causes blood vessels to narrow from binding to receptors in tissues, causing relaxation of blood vessels and reducing blood pressure. It is used to manage hypertension, treat congestive heart failure, and diabetic nephropathy. It is an important component in the formulation of medicine that treats cardiovascular diseases and diseases related to hypertension. Its application is utilized in the healthcare industry, where it is widely prescribed by healthcare professionals to patients.

Industrial Irbesartan procurement is affected by its growing demand in cardiovascular diseases, kidney problems, and hypertension. A rise in the aging population with a higher incidence of health issues contributes to its demand. Better healthcare access in developing regions enhances the diagnosis and treatment of hypertension, leading to increased demand for antihypertensive medications like irbesartan. Ongoing research into the drug's efficacy for conditions beyond hypertension, such as diabetic nephropathy, also contributes to market growth through expanded therapeutic indications. Altogether, these factors, along with advancements in technology and its chemical and therapeutic benefits, contribute to its overall market.

Raw Material for Irbesartan Production

According to the Irbesartan manufacturing plant project report, the key raw materials used in the production of Irbesartan include 4'-Methyl-Biphenyl-2-Carboxylic Acid-Sodium Azide-Butyl Spirononanone Hydrochloride.

Manufacturing Process of Irbesartan

The extensive Irbesartan production cost report consists of the following major industrial manufacturing process:

1. From 4'-Methyl-Biphenyl-2-Carboxylic Acid, Sodium Azide, and Butyl Spirononanone Hydrochloride: The manufacturing process of Irbesartan involves several steps. First, the bromination of 4'-Methyl-biphenyl-2-carboxylic acid takes place by adding a bromine atom to it. After that, a tetrazole ring is formed through a reaction with sodium azide followed by condensation with a spiro compound like butyl spironolactone hydrochloride, leading to the formation of a spiro compound. Finally, the spiro compound is coupled with 1-Benzyl-5-(4'-bromomethyl-biphenyl-2-yl)-1H-tetrazole forming Irbesartan as the final product.

Irbesartan has a molecular formula of C25H28N6O and a molecular weight of 428.5 g/mol. It is a white to off-white crystalline powder with no odor. It is insoluble in water but shows slight solubility in methylene chloride and alcohol. Its melting point is in the range of 180-181 °C with a boiling point of 648.6 °C. Its density value is 1.30 g/cm³ and shows stability under moderate temperatures. It has high thermal stability, essential for processing and formulation and its bioavailability ranges from 60% to 80%. These chemical and physical properties make it useful in clinical and pharmaceutical properties.