Isoxazole Production Cost Reports

The report provides a detailed analysis essential for establishing an Isoxazole manufacturing plant. It encompasses all critical aspects necessary for Isoxazole production, including the cost of Isoxazole production, Isoxazole plant cost, Isoxazole production costs, and the overall Isoxazole manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating an Isoxazole production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Isoxazole is an organic component that is found in natural products and bioactive molecules. The compound is widely used as a medication for the treatment of UTIs, Alzheimer’s disease, cancer, and various bacterial and fungal infections due to its effective anti-bacterial and anti-inflammatory activities. Moreover, isoxazole and its derivatives are also utilized as an insecticide for managing Callosobruchus chinensis and controlling other pests to protect crops in the agricultural field.

The market of Isoxazole is largely led by its application for the treatment of various bacterial and fungal infections, including UTIs, and certain neurological disorders, which remarkably promotes its demand in the medical and pharmaceutical industries. Moreover, its usage in the manufacture of Isoxazole-based pharmaceutical drugs due to its potential anti-cancer, anti-viral, and immunomodulatory effects further promote its market expansion. Additionally, its employment as an insecticide and an herbicide to get rid of insects and pests in the agriculture field effectively boosts its demand in the agrochemical industry. Furthermore, several factors influence industrial Isoxazole procurement, such as the availability of raw materials (N-Butyllithium, etc.), cost and pricing, regulatory compliance, quality standards, technological advancements, environmental considerations, sustainability practices, distribution (including trading and shipping), logistics, safety standards, etc.

Raw Material for Isoxazole Production

According to the Isoxazole manufacturing plant project report, the major raw materials for Isoxazole production include Nitrile Oxides-Terminal Alkyne; Terminal Alkyne-N-Butyllithium (n-BuLi).

Manufacturing Process of Isoxazole

The extensive Isoxazole production cost report consists of the following industrial manufacturing process:

• Production via Cycloaddition Reaction: This method of production is initiated by the cycloaddition reaction of various nitrile oxides and terminal alkynes by using Cu(I) as the catalyst, which results in the formation of a series of 3,5-disubstituted isoxazoles as the product. This method of utilizing the cycloaddition strategy has shown to be a successful way to prepare isoxazoles with improved yield and regioselectivity.
• Production form n-BuLi (n-Butyllithium):  This method of production involves the chemical reaction of terminal alkynes with n-BuLi in the presence of THF, followed by a reaction with an aromatic aldehyde and molecular iodine to form an intermediate product. Further, this obtained intermediate is treated with hydrazine or hydroxylamine to obtain isoxazole as the final product. This method also produces isoxazole in high yield and increased regioselectivity.

Isoxazole is a five-membered ring compound that is the parent member of the class of isoxazoles. The molecular formula of the compound is C3H3NO, and its molar mass is 69.06 g/mol. Moreover, the IUPAC name of the compound is 1,2-oxazole. The compound is also known as 1-Oxa-2-azacyclopentadiene and 2-azafuran. The structure of isoxazole is composed of a nitrogen atom and an oxygen atom adjacent to each other. Additionally, the pKa value of isoxazole is -3.0, and its melting point is 93-95 degrees Celsius.