Ketoprofen Production Cost Reports

The report provides a detailed analysis essential for establishing a Ketoprofen manufacturing plant. It encompasses all critical aspects necessary for Ketoprofen production, including the cost of Ketoprofen production, Ketoprofen plant cost, Ketoprofen production costs, and the overall Ketoprofen manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Ketoprofen production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Ketoprofen is a non-steroidal anti-inflammatory agent (NSAIA) widely known for its antipyretic and analgesic properties. It is widely utilized as an oral medication for the treatment of rheumatoid arthritis, myelitis, chronic arthritis, ankylosing spondylitis, and gout due to its potential anti-inflammatory effects and mild adverse reactions. Moreover, it also finds its application in the treatment of acute pain and other symptoms associated with various inflammatory diseases. Additionally, it is often employed as a medication for the treatment of inflammation and pain associated with musculoskeletal disorders in horses, dogs, and other animals.

The demand for Ketoprofen is primarily driven due to its key role as a nonsteroidal anti-inflammatory drug (NSAID), which remarkably promotes its market growth. Moreover, its application for the treatment of rheumatoid and osteoarthritis, and other inflammatory symptoms further boosts its demand in the medical and pharmaceutical industries. Additionally, its usage as a medicine for alleviating pain due to inflammatory diseases in animals, such as horses, etc., significantly enhances its demand in the veterinary medicine industry. Furthermore, several factors, such as the availability of raw materials (3-methylbenzophenone), cost, compliance with medical regulations, scientific advancements, and quality standards, significantly influence industrial Ketoprofen procurement globally.

Raw Material for Ketoprofen Production

According to the Ketoprofen manufacturing plant project report, the major raw material for Ketoprofen production includes 3-Methylbenzophenone.

Manufacturing Process of Ketoprofen

The extensive Ketoprofen production cost report consists of the following industrial manufacturing process:

1. Production from 3-Methylbenzophenone: This method of production is initiated by the bromination of 3-methylbenzophenone, which produces 3-bromo-methylbenzophenone. Further, the obtained compound undergoes reduction by using sodium cyanide to give 3-cyanomethylbenzophenone, followed by its reaction with the diethyl ester of carbonic acid in the presence of sodium ethoxide to synthesize cyanoacetic ester derivative. Further, the obtained cyanoacetic ester compound is subjected to alkylation by using methyl iodide, followed by acidic hydrolysis, which results in the formation of ketoprofen as the final product.

Ketoprofen belongs to the class of benzophenones. The compound is an oxo monocarboxylic acid that serves as a nonsteroidal anti-inflammatory drug (NSAID). The molecular formula of the compound is C16H14O3, and its molar mass is 254.28 g/mol. The compound is a drug that finds huge applications in the medical industry for the treatment of arthritis. It is mainly sold under the trade name Orudis. Moreover, the boiling point of the compound is 357.5°C, and its melting point ranges between 93-96°C. The density of the compound is 1.1565 g/cm3, and its solubility in water is 209 mg/L at low temperatures. Additionally, the compound exists in the form of a white crystalline powder that is stored between 2-8°C. The chemical name of the compound is 2-(3-benzoyl)propionic acid.