Linagliptin Production Cost Reports
Healthcare
The report provides a detailed analysis essential for establishing a Linagliptin manufacturing plant. It encompasses all critical aspects necessary for Linagliptin production, including the cost of Linagliptin production, Linagliptin plant cost, Linagliptin production costs, and the overall Linagliptin manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Linagliptin production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Linagliptin is an oral antihyperglycemic drug used to treat type-2 diabetes mellitus. It increases the level of a hormone called incretin. This mechanism of action increases the secretion of insulin and decreases the level of glucagon in the blood circulation. It is also used with other hypoglycemic drugs such as Metformin and Sulfonylureas, which increases its role in controlling the blood glucose levels in patients with type-2 diabetes mellitus. Thus, it finds its application in the pharmaceutical and medical industries.
The procurement of Linagliptin is influenced by its application in the pharmaceutical and medical industries to treat type-2 diabetes mellitus. It is used as an oral antihyperglycemic to increase the secretion of insulin and decrease the level of glucagon in patients. The global demand for Linagliptin has increased due to the increasing cases of type-2 diabetes mellitus. The aging population, along with poor diet and disturbed lifestyle, has also increased the demand for antidiabetic drugs such as Linagliptin. It is also used with other antidiabetic drugs such as Metformin and Sulfonylureas, which increases its role in controlling the blood glucose levels in patients, thus increasing its market growth.
It is available as an oral drug which makes it easy to intake and enhances patient compliance. Healthcare and technological advancements provide better accessibility for antidiabetic drugs such as Linagliptin, which further drives its market. It is known to show fewer side effects, which makes it safe to be used for longer periods. Overall, the industrial Linagliptin procurement is influenced by its applications in the pharmaceutical and medical industries, the increase in the cases of type-2 diabetes, the aging population, its use with other antidiabetic drugs, fewer side effects, healthcare and technological advancements, patient compliance, cost-effectiveness, research and development, logistics and distribution, and regulatory approvals.
Raw Material for Linagliptin Production
According to the Linagliptin manufacturing plant project report, the key raw material used in the production of Linagliptin include 1-(2-aminophenyl)ethenone.
Manufacturing Process of Linagliptin
The extensive Linagliptin production cost report consists of the following major industrial manufacturing process:
- Production from 1-(2-aminophenyl)ethenone: The manufacturing process of Linagliptin involves a cyclization reaction of 1-(2-aminophenyl)ethanone and 2-chloroacetonitrile in the presence of Hydrogen chloride to form an intermediate. The intermediate is then treated with 8-bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione in the presence of sodium carbonate to produce another intermediate. Furthermore, the intermediate undergoes a condensation reaction with (R)-2-(piperidin-3-yl)isoindoline-1,3-dione D-(−)-tartaric acid using diisopropylethylamine, to obtain a compound. Finally, this compound is subjected to aminolysis with ethanolamine to yield Linagliptin.
Linagliptin, commercially known as Tradjenta, is a white-to-yellow crystalline solid, having the molecular formula C25H28N8O2 and a molecular weight of 472.5 g/mol. Its melting point is 202 °C. Its water solubility is <1 mg/mL. Its pKa value is 9.86. It is soluble in soluble in methanol, sparingly soluble in ethanol, and slightly soluble is isopropanol. It is stable at normal conditions; however, it should be avoided from oxidizing agents. It is slightly hygroscopic. Linagliptin is an oral antihyperglycemic drug. It is a DPP-4 inhibitor used to treat type-2 diabetes mellitus by increasing the secretion of insulin and decreasing the levels of glucagon.
Product Details
| Particulars | Details |
|---|---|
| Product Name | Linagliptin |
| Scope | Manufacturing Process: Process Flow, Material Flow, Material Balance Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital Variable Cost: Raw Material, Utilities, Other Variable Costs Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs Financing Costs: Interest on Working Capital, Interest on Loans Other Costs: Depreciation Charges, General Sales and Admin Cost |
| Currency | US$ (Data can also be provided in the local currency) |
| Pricing and Purchase Options | Basic: US$ 2499 Premium: US$ 3499 Enterprise: US$ 4799 |
| Customization Scope | The report can be customized as per the requirement of the customer |
| Post-Sale Analysts Report | 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable |
| Delivery Format | PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request) |
How does our Linagliptin Production Cost Report Provide Exhaustive Data and Extensive Insights?
At Procurement Resource, we not only focus on optimizing the should cost of production for Linagliptin but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.
We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Linagliptin market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.
Key Questions Answered in This Report
- What are the key requirements for setting up a Linagliptin manufacturing plant?
- How is Linagliptin manufactured?
- What is the process flow involved in producing Linagliptin?
- What are the raw material requirements and costs for producing Linagliptin?
- What is the total size of land required for setting up a Linagliptin manufacturing plant?
- What are the construction requirements for setting up a Linagliptin manufacturing plant?
- What are the machinery requirements for producing Linagliptin?
- What are the utility requirements and costs for producing Linagliptin?
- What are the manpower requirements for producing Linagliptin?
- What are the average salaries/wages of manpower working in a Linagliptin manufacturing plant?
- What are the packaging requirements and associated costs for Linagliptin?
- What are the transportation requirements and associated costs for Linagliptin?
- What are the capital costs for setting up a Linagliptin manufacturing plant?
- What are the operating costs for setting up a Linagliptin manufacturing plant?
- What should be the price of Linagliptin?
- What will be the income and expenditures for a Linagliptin manufacturing plant?
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