Lisinopril Production Cost Reports
Healthcare
The report provides a detailed analysis essential for establishing a Lisinopril manufacturing plant. It encompasses all critical aspects necessary for Lisinopril production, including the cost of Lisinopril production, Lisinopril plant cost, Lisinopril production costs, and the overall Lisinopril manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Lisinopril production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor used to treat hypertension, heart failure, and myocardial infarction. It inhibits the angiotensin-converting enzyme, thus preventing the conversion of angiotensin I to angiotensin II, which is a potent vasoconstrictor. It also inhibits the renin-angiotensin-aldosterone (RAAS) system. Additionally, Lisinopril is also used to manage diabetic neuropathy by reducing proteinuria (elevated levels of protein in the urine) and protecting kidney function. It is also functional in managing proteinuric chronic kidney disease and has its use in post-transplant erythrocytosis.
The procurement for Lisinopril is influenced by its therapeutic applications in the pharmaceutical and medical industries as a potent and effective antihypertensive drug used to treat hypertension, heart failure, myocardial infarction, and other cardiovascular ailments. Additionally, its use in conditions such as diabetic neuropathy and proteinuric chronic kidney disease contributes to its growing market presence. The widespread occurrence of hypertension and heart diseases and an aging population boosts the demand for Lisinopril. It is also recommended in post-heart attack recovery. Its cost-effectiveness as a generic medication enhances its market appeal.
The improvement in the drug-delivery system further boosts its industrial significance. Conclusively, the industrial Lisinopril procurement is influenced by its therapeutic applications in pharmaceutical and medical industries, its off-label uses, increased prevalence of hypertension and heart diseases, cost-effectiveness, market dynamics, logistics and distribution, advancement in healthcare, and regulatory approvals.
Raw Material for Lisinopril Production
According to the Lisinopril manufacturing plant project report, the key raw material used in the production of Lisinopril includes L-lysine.
Manufacturing Process of Lisinopril
The extensive Lisinopril production cost report consists of the following major industrial manufacturing process:
- Production from L-lysine: The manufacturing process of Lisinopril involves several steps. In the first step, L-lysine reacts with ethyl trifluoroacetate to produce N6-trifluoroacetyl-L-lysine. This compound is then treated with triphosgene to form N6-trifluoroacetyl-N2-carboxy-L-lysine anhydride, which is further condensed with L-proline to obtain N6-trifluoroacetyl-L-lysyl-L-proline (intermediate). This intermediate is further condensed with ethyl 2-oxo-4-phenylbutyrate and hydrogenated using a Raney-Nickel catalyst to produce N2-(1-(S)-ethoxycarbonyl-3-phenylpropyl)-L-N6-(trifluoroacetyl)-L-lysyl-L-proline. Finally, this compound is hydrolyzed with sodium hydroxide to yield Lisinopril.
Lisinopril is a white to off-white, odourless crystalline powder having the molecular formula C21H31N3O5 and a molecular weight of 405.5 g/mol. It is soluble in water, slightly soluble in ethanol, and practically insoluble in organic solvents such as chloroform and ether. Its melting point is 148 °C. It has a pKa value of 2.5 (at 25 °C). Its common name is Zestril. Lisinopril is a potent antihypertensive drug used to treat hypertension and heart problems by inhibiting the angiotensin-converting enzyme and renin-angiotensin-aldosterone system.
Product Details
| Particulars | Details |
|---|---|
| Product Name | Lisinopril |
| Scope | Manufacturing Process: Process Flow, Material Flow, Material Balance Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital Variable Cost: Raw Material, Utilities, Other Variable Costs Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs Financing Costs: Interest on Working Capital, Interest on Loans Other Costs: Depreciation Charges, General Sales and Admin Cost |
| Currency | US$ (Data can also be provided in the local currency) |
| Pricing and Purchase Options | Basic: US$ 2499 Premium: US$ 3499 Enterprise: US$ 4799 |
| Customization Scope | The report can be customized as per the requirement of the customer |
| Post-Sale Analysts Report | 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable |
| Delivery Format | PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request) |
How does our Lisinopril Production Cost Report Provide Exhaustive Data and Extensive Insights?
At Procurement Resource, we not only focus on optimizing the should cost of production for Lisinopril but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.
We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Lisinopril market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.
Key Questions Answered in This Report
- What are the key requirements for setting up a Lisinopril manufacturing plant?
- How is Lisinopril manufactured?
- What is the process flow involved in producing Lisinopril?
- What are the raw material requirements and costs for producing Lisinopril?
- What is the total size of land required for setting up a Lisinopril manufacturing plant?
- What are the construction requirements for setting up a Lisinopril manufacturing plant?
- What are the machinery requirements for producing Lisinopril?
- What are the utility requirements and costs for producing Lisinopril?
- What are the manpower requirements for producing Lisinopril?
- What are the average salaries/wages of manpower working in a Lisinopril manufacturing plant?
- What are the packaging requirements and associated costs for Lisinopril?
- What are the transportation requirements and associated costs for Lisinopril?
- What are the capital costs for setting up a Lisinopril manufacturing plant?
- What are the operating costs for setting up a Lisinopril manufacturing plant?
- What should be the price of Lisinopril?
- What will be the income and expenditures for a Lisinopril manufacturing plant?
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