Lopinavir Production Cost Reports
Healthcare
The report provides a detailed analysis essential for establishing a Lopinavir manufacturing plant. It encompasses all critical aspects necessary for Lopinavir production, including the cost of Lopinavir production, Lopinavir plant cost, Lopinavir production costs, and the overall Lopinavir manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Lopinavir production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Lopinavir is an antiretroviral drug that is used to inhibit HIV protease, responsible for the replication of HIV. It is extensively used in combination with Ritonavir (under the brand name Kaletra) to treat HIV-1 infection. It has also been used to treat other viral infections, such as SARS-CoV-2, during the COVID-19 pandemic. Moreover, it also finds its applications in veterinary medicine for the treatment of viral infections in animals.
The procurement of Lopinavir is influenced by its applications in the medical and pharmaceutical industries as an antiretroviral drug used to inhibit HIV protease enzyme for the treatment of HIV/AIDS. The increase in the incidence rate of HIV infection directly affects the demand for Lopinavir worldwide. The extensive use of Lopinavir in new infectious diseases and pandemics such as COVID-19 increases its procurement demand.
Its utilization in research to modify treatment strategies and develop new drugs functioning as protease inhibitors drives up its demand. Additionally, its efficacy in treating viral infections in animals boosts its demand in the veterinary industry. Conclusively, industrial lopinavir procurement is influenced by its therapeutic efficacy in medical and pharmaceutical industries, extensive use in pandemics and outbreaks, applications in the veterinary industry, its use in research investigations, along the cost of the raw materials, market dynamics, regulatory approvals, logistics and distribution, technological advancements, and economic factors.
Raw Material for Lopinavir Production
According to the Lopinavir manufacturing plant project report, the key raw material used in the production of Lopinavir includes (2S, 3S, 5S)- 5-Amino-2-(dibenzylamino)-1,6-diphenylhexane-3-ol.
Manufacturing Process of Lopinavir
The extensive Lopinavir production cost report consists of the following major industrial manufacturing processes:
- Production from (2S, 3S, 5S)- 5-Amino-2-(dibenzylamino)-1,6-diphenylhexane-3-ol: The production process for Lopinavir involves several key steps. First, (2S, 3S, 5S)- 5-Amino-2-(dibenzylamino)-1,6-diphenylhexane-3-ol is activated using N,N-carbonyldiimidazole. The activated form is then reacted with (2S)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl) butanoic acid to form an intermediate. Further, this intermediate is subjected to debenzylation with ammonium formate and palladium on charcoal to create another intermediate. Following this, the intermediate is treated with L-pyroglutamic acid to yield a salt. In the final step, the salt undergoes a chemical reaction with (2,6-dimethylphenoxy)acetic acid to yield Lopinavir.
Lopinavir is a white to off-white crystalline powder having the molecular formula C37H48N4O5. Its molecular weight is around 628.8 g/mol. Its melting point is approximately 124-127 °C. It is practically insoluble in water but soluble in ethanol, methanol, and isopropanol. The IUPAC name of Lopinavir is (2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide. Lopinavir inhibits the replication and multiplication of HIV virus, by inhibiting HIV protease enzyme. It is commonly used in combination with Ritonavir for the treatment of HIV/AIDS.
Product Details
Particulars | Details |
---|---|
Product Name | Lopinavir |
Scope | Manufacturing Process: Process Flow, Material Flow, Material Balance Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital Variable Cost: Raw Material, Utilities, Other Variable Costs Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs Financing Costs: Interest on Working Capital, Interest on Loans Other Costs: Depreciation Charges, General Sales and Admin Cost |
Currency | US$ (Data can also be provided in the local currency) |
Pricing and Purchase Options | Basic: US$ 2499 Premium: US$ 3499 Enterprise: US$ 4799 |
Customization Scope | The report can be customized as per the requirement of the customer |
Post-Sale Analysts Report | 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable |
Delivery Format | PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request) |
Key Questions Answered in This Report
- What are the key requirements for setting up a Lopinavir manufacturing plant?
- How is Lopinavir manufactured?
- What is the process flow involved in producing Lopinavir?
- What are the raw material requirements and costs for producing Lopinavir?
- What is the total size of land required for setting up a Lopinavir manufacturing plant?
- What are the construction requirements for setting up a Lopinavir manufacturing plant?
- What are the machinery requirements for producing Lopinavir?
- What are the utility requirements and costs for producing Lopinavir?
- What are the manpower requirements for producing Lopinavir?
- What are the average salaries/wages of manpower working in a Lopinavir manufacturing plant?
- What are the packaging requirements and associated costs for Lopinavir?
- What are the transportation requirements and associated costs for Lopinavir?
- What are the capital costs for setting up a Lopinavir manufacturing plant?
- What are the operating costs for setting up a Lopinavir manufacturing plant?
- What should be the price of Lopinavir?
- What will be the income and expenditures for a Lopinavir manufacturing plant?
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