Lorazepam Production Cost Reports

Healthcare

The report provides a detailed analysis essential for establishing a Lorazepam manufacturing plant. It encompasses all critical aspects necessary for Lorazepam production, including the cost of Lorazepam production, Lorazepam plant cost, Lorazepam production costs, and the overall Lorazepam manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Lorazepam production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Lorazepam is a popular short-acting benzodiazepine used as a sedative and anxiolytic for treating seizures, severe anxiety, and panic disorders. The US Food and Drug Administration (FDA) has approved Lorazepam for the short-term treatment of anxiety symptoms related to anxiety disorders, anxiety-related insomnia, adult anesthesia premedication to induce sedation or amnesia or relieve anxiety, and the management of status epilepticus.

The procurement of Lorazepam is influenced by its application in the pharmaceutical and medical industries as a sedative and anxiolytic to treat various symptoms related to anxiety disorder. The need for Lorazepam is increasing as cases of anxiety disorders are on the rise. It witnesses a significant demand from the aging population as they are more likely to be affected by anxiety and sleep disorders. Lorazepam is used off-label for various conditions such as sleeplessness, panic disorder, delirium, alcohol withdrawal syndrome, vertigo, chemotherapy-associated anticipatory nausea, and vomiting (adjunct or breakthrough), delirium, and psychogenic catatonia, thus increasing its demand.

In several clinical settings, Lorazepam is utilized in comparison to other benzodiazepines. Clinicians use it in acute, short-term, and long-term contexts, ranging in specialization and practice level. Because it acts quickly (in 1-3 minutes when administered intravenously), it is used in hospital settings. Therefore, the industrial Lorazepam procurement is influenced by its application in the pharmaceutical and medical industries as a sedative and anxiolytic, the rising cases of anxiety and sleep disorders, the aging population, its wide range of applications, its off-label uses, quick onset of action, clinical uses, fewer side effects, along with cost-effectiveness, increasing awareness among individuals regarding mental health, research and development, and regulatory approvals.

Raw Material for Lorazepam Production

According to the Lorazepam manufacturing plant project report, the key raw material used in the production of Lorazepam includes 2-amino-2′,5-dichlorobenzophenone.

Manufacturing Process of Lorazepam

The extensive Lorazepam production cost report consists of the following major industrial manufacturing process:

  • Production from 2-amino-2′,5-dichlorobenzophenone: The manufacturing process of Lorazepam starts with the N-acylation of 2-amino-2′,5-dichlorobenzophenone in the presence of chloroacetyl chloride and toluene to form a chloro intermediate. The chloro intermediate is subjected to cyclization using hexamine and NH4OAc to form delorazepam. In the next step, delorazepam is oxidized with m-chloroperbenzoic acid to form an N-oxide intermediate. The delorazepam N-oxide intermediate is treated with acetic anhydride, and to this mixture, NH4OH and ethanol are added, which finally gives Lorazepam.

Lorazepam, commercially known as Ativan, is a white powder having the molecular formula C15H10Cl2N2O2 and a molecular weight of 321.2 g/mol. It has a boiling point of 533.8 °C at 760 mm Hg and a melting point in the range of 192-194 °C. It has a log P value of 2.39. The value of its dissociation constant, pKa, is 13. It is highly soluble in water with a solubility of 80 mg/L. It also dissolves in organic solvents such as ethanol and methanol. It is a member of the class of medications called benzodiazepines, used to treat a variety of symptoms related to anxiety disorders.

Product Details

Particulars Details
Product Name Lorazepam
Scope Manufacturing Process: Process Flow, Material Flow, Material Balance

Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation

Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital

Variable Cost: Raw Material, Utilities, Other Variable Costs

Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs

Financing Costs: Interest on Working Capital, Interest on Loans

Other Costs: Depreciation Charges, General Sales and Admin Cost
Currency US$ (Data can also be provided in the local currency)
Pricing and Purchase Options Basic: US$ 2499
Premium: US$ 3499
Enterprise: US$ 4799
Customization Scope The report can be customized as per the requirement of the customer
Post-Sale Analysts Report 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable
Delivery Format PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request)

How does our Lorazepam Production Cost Report Provide Exhaustive Data and Extensive Insights?

At Procurement Resource, we not only focus on optimizing the should cost of production for Lorazepam but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.

We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Lorazepam market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.

Key Questions Answered in This Report

  • What are the key requirements for setting up a Lorazepam manufacturing plant?
  • How is Lorazepam manufactured?
  • What is the process flow involved in producing Lorazepam?
  • What are the raw material requirements and costs for producing Lorazepam?
  • What is the total size of land required for setting up a Lorazepam manufacturing plant?
  • What are the construction requirements for setting up a Lorazepam manufacturing plant?
  • What are the machinery requirements for producing Lorazepam?
  • What are the utility requirements and costs for producing Lorazepam?
  • What are the manpower requirements for producing Lorazepam?
  • What are the average salaries/wages of manpower working in a Lorazepam manufacturing plant?
  • What are the packaging requirements and associated costs for Lorazepam?
  • What are the transportation requirements and associated costs for Lorazepam?
  • What are the capital costs for setting up a Lorazepam manufacturing plant?
  • What are the operating costs for setting up a Lorazepam manufacturing plant?
  • What should be the price of Lorazepam?
  • What will be the income and expenditures for a Lorazepam manufacturing plant?

Need more help?

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