Loxoprofen Sodium Production Cost Reports

The report provides a detailed analysis essential for establishing a Loxoprofen Sodium manufacturing plant. It encompasses all critical aspects necessary for Loxoprofen Sodium production, including the cost of Loxoprofen Sodium production, Loxoprofen Sodium plant cost, Loxoprofen Sodium production costs, and the overall Loxoprofen Sodium manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Loxoprofen Sodium production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Loxoprofen Sodium is a non-steroidal medication (NSAID) FDA-approved drug that finds huge applications in the medical and pharmaceutical industries. It is widely utilized as an anti-inflammatory agent in the treatment and management of osteoarthritis, rheumatoid arthritis, and other inflammatory disorders. Moreover, it also finds its application in the treatment of toothaches, headaches, menstrual pain, and musculoskeletal pain (including arthritis and back pain). Additionally, it is also employed as a medication in reducing fever.

The market for Loxoprofen Sodium is majorly driven by its utilization as an analgesic medication to manage pain associated with various conditions, such as headaches and musculoskeletal pain, which significantly boosts its demand in the pharmaceutical industry. Moreover, its employment as an over-the-counter (OTC) medicine for relieving general pain, including muscle pain, joint pain, etc., further enhances its demand in the medical and pharmaceutical industries. Additionally, variations in its cost and the availability of raw materials (loxoprofen impurity 11, etc.), regulatory compliance, and pharmaceutical regulations serve as major factors in outlining procurement guidelines. Moreover, technological advancements in the production process, supplier reliability, sustainability practices, and efficient logistics largely impact industrial Loxoprofen sodium procurement globally.

Raw Material for Loxoprofen Sodium Production

According to the Loxoprofen Sodium manufacturing plant project report, the major raw materials for Loxoprofen Sodium production include loxoprofen impurity 11-Sodium Hydroxide.

Manufacturing Process of Loxoprofen Sodium

The extensive Loxoprofen Sodium production cost report consists of the following industrial manufacturing process:

1. Production from Loxoprofen Impurity 11: This method of production involves the use of loxoprofen impurity 11 as the starting material for the preparation of loxoprofen sodium as the final product. The process is initiated by adding loxoprofen impurity 11 or Methyl 2-(4-((2-oxocyclopentyl)methyl)phenyl) propionate into a 500 ml three-necked flask along with ethanol and refluxed, followed by the addition of sodium hydroxide solution dropwise for 1 hour. Further, the obtained material is concentrated and dried to form a residue, which is recrystallized from ethanol-methyl tert-butyl ether to obtain a white powdery solid, i.e., loxoprofen sodium, as the final product.

Loxoprofen Sodium is an organic sodium salt that serves as a drug that has anti-inflammatory and antipyretic agents. The molecular formula of the compound is C15H17NaO3, and its molecular weight is 268.28 g/mol. Moreover, the compound is mainly marketed under the brand name Loxonin. The melting point of the compound is 202-206°C, and its boiling point is 417.9°C. Additionally, it appears as a white solid that is soluble in DMSO. It is stored in an inert atmosphere at room temperature. This drug might have some side effects, including nausea, vomiting, bleeding, anemia, anorexia, diarrhea, and constipation.