Lurasidone Production Cost Reports

The report provides a detailed analysis essential for establishing a Lurasidone manufacturing plant. It encompasses all critical aspects necessary for Lurasidone production, including the cost of Lurasidone production, Lurasidone plant cost, Lurasidone production costs, and the overall Lurasidone manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Lurasidone production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Lurasidone is a member of the second-generation antipsychotic class of drugs. It is a benzothiazole used in the treatment of schizophrenia and bipolar depression. Lurasidone exhibits moderate agonistic properties at the serotonin 5-HT1A receptor and full antagonistic properties at the dopamine D2 and serotonin 5-HT2A and 5-HT7 receptors. Lurasidone is occasionally used to treat irritability, rage, and bipolar mania in people with autism spectrum disorder. Thus, it finds its application in the pharmaceutical and medical industries.

The procurement of Lurasidone is influenced by its application in the pharmaceutical and medical industries as an antipsychotic medication used to treat schizophrenia and bipolar disorders. The need for Lurasidone is increasing as cases of psychotic disorders are on the rise. It witnesses a significant demand from the aging population as they are more likely to be affected by schizophrenia and other psychotic disorders. The FDA has also approved Lurasidone for the treatment of bipolar depression; this is a major innovation since Lurasidone is the first medication to be approved for use as a lithium or valproate adjunct as well as a monotherapy to treat bipolar disorders, thus increasing its demand.

Lurasidone exhibits the highest binding affinity for the 5-HT7 receptor when compared to other atypical antipsychotics, which increases its demand. When compared to other antipsychotics, Lurasidone is known to have a more favorable side effect profile, which is why patients and healthcare professionals prefer it. Overall, the industrial Lurasidone procurement is influenced by its application in the pharmaceutical and medical industries as an antipsychotic medication to treat schizophrenia and bipolar disorders, the rising cases of psychotic and mental disorders, the aging population, its use with other drugs, the wide range of applications, highest binding affinity, along with cost-effectiveness, increasing mental health awareness among individuals, fewer side effects, research and development, and regulatory approvals.

Raw Material for Lurasidone Production

According to the Lurasidone manufacturing plant project report, the key raw material used in the production of Lurasidone include 4'-(1,2-Benzisothiazol-3-yl)octahydrospiro[2H-isoindole-2,1'-piperaziniuM]Methanesulfonate.

Manufacturing Process of Lurasidone

The extensive Lurasidone production cost report consists of the following major industrial manufacturing process:

• Production from 4'-(1,2-Benzisothiazol-3-yl)octahydrospiro[2H-isoindole-2,1'-piperaziniuM]Methanesulfonate: The manufacturing process of Lurasidone involves a two-step process. The first step involves the condensation of 4'-(1,2-Benzisothiazol-3-yl)octahydrospiro[2H-isoindole-2,1'-piperaziniuM]Methanesulfonate and 4,7 -Methano-1H-isoindole-1,3(2H)-dione with potassium carbonate and then the mixture is suspended in toluene. The suspension is heated at ambient temperature, and after the completion of the reaction, it is cooled at room temperature to form Lurasidone.

Lurasidone, commercially known as Latuda, is a white to off-white crystalline powder, having the molecular formula C28H36N4O2S and a molecular weight of 492.7 g/mol. Its water solubility is 0.00789 mg/mL. It dissolves in methanol, slightly dissolves in ethanol, dissolves in some extent in acetone and water, and is insoluble in 0.1 N HCl and toluene. Its log P value is 5.25. Its pKa value is 8.5. It is an antipsychotic medication used to treat mental disorders such as schizophrenia and bipolar disorders.