Methaqualone Production Cost Reports

The report provides a detailed analysis essential for establishing a Methaqualone manufacturing plant. It encompasses all critical aspects necessary for Methaqualone production, including the cost of Methaqualone production, Methaqualone plant cost, Methaqualone production costs, and the overall Methaqualone manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Methaqualone production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Methaqualone is a sedative that improves sleep disorders and muscle spasms. It’s a popular drug that calms the Nervous System and has been in use since the 1970s. The active ingredient binds to GABA-A receptors of the brain and suppresses its effects on neural excitability, resulting in sedation. This results in drowsiness , muscle relaxation, and anxiolysis. It is used to induce deep sleep in people with insomnia and is much better than barbiturates. Its action enables it to relieve muscle spasms by relaxing muscles. Apart from that, Methaqualone is also used as an antianxiety medicine to decrease anxiety levels among patients. This drug is commonly used for sedating but highly abused as well as illicitly produced, hence the need for strict controls over it together with controlled drugs.

The primary drivers behind Methaqualone are its medical applications, mainly for the treatment of insomnia, muscle spasms, and anxiety disorders. It’s given to insomniacs who have trouble falling asleep due to various reasons. In addition, the drug acts as a muscle relaxant, thereby relieving muscle spasms, whereas its anxiolytic nature helps lower anxiety levels among patients suffering from this condition. So, the developments in its demand as a sedative, along with its production prices, market prices, and logistics, directly influence industrial Methaqualone procurement in the market across the globe.

Raw Material for Methaqualone Production

According to the Methaqualone manufacturing plant project report, the key raw materials used in the production of Methaqualone include Anthranilic Acid-Acetone-Formamide.

Manufacturing Process of Methaqualone

The extensive Methaqualone production cost report consists of the following major industrial manufacturing process:

• From Anthranilic Acid, Acetone, and Formamide: The manufacturing process for Methaqualone involves several key steps. The anthranilic acid derivative is first condensed with acetone, forming an imine intermediate. The process continues through the cyclization of this intermediate, using an acid catalyst to give the quinazolinone structure. Thus, 2-methyl-3-phenyl-4(3H)-quinazolinone is obtained by the addition of methyl and phenyl groups. The impure product is then dissolved in a solvent and purified using crystallization or chromatography to yield Methaqualone.

Methaqualone is a white to off-white crystalline powder. Its molecular formula is C16H14N2O, and it has a molecular weight of 250.30 g/mol. It has a melting point of 120°C and a density of around 1.16 g/cm³. It is practically insoluble in water but soluble in ethanol, ether, and chloroform. It shows UV spectrum at 225, 263, 304, and 316 nm. It is moderately lipophilic, having a log P value from 2.54 to 3.17. It is often found in its hydrochloride salt form, which has a melting point of 255-265°C. All these properties contribute to its pharmacology applications.