Metronidazole Production Cost Reports

The report provides a detailed analysis essential for establishing a metronidazole manufacturing plant. It encompasses all critical aspects necessary for metronidazole production, including the cost of metronidazole production, metronidazole plant cost, metronidazole production costs, and the overall metronidazole manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a metronidazole production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Metronidazole is an antibiotic and a synthetic antiprotozoan drug that is commonly used to treat a wide variety of infections. It is majorly utilized for the treatment of gastrointestinal infections and certain parasitic infections, which include giardiasis, amoebic dysentery, and trichomoniasis. Moreover, it is also employed in aquaculture to control pathogens and enhance survival rates. Additionally, it also finds its application as a topical ointment for the treatment of inflammatory lesions and other skin infections.

The market for metronidazole is primarily driven by its wide usage as an antibiotic and antiprotozoal medicine for the treatment of infections in humans and animals, which significantly boosts its demand in the pharmaceutical and veterinary medicine industry. Moreover, its employment as an antitrichomonal drug for the treatment of infected gums, dental abscesses, bacterial vaginosis, and pelvic inflammatory disease effectively increases its demand in the medical and pharmaceutical industries.

Additionally, its application in aquaculture to control diseases and increase production further enhances its demand in the fisheries and aquatic farming industry. Its utilization in the healthcare and personal care industry as a topical gel further accentuates its market growth. Furthermore, several factors influence industrial metronidazole procurement, such as the availability of raw materials, cost, and pricing, compliance with pharmaceutical regulations, quality standards, technological advancements, environmental considerations, sustainability practices, distribution (including trading and shipping), logistics, safety standards, etc.

Raw Material for Metronidazole Production

According to the Metronidazole manufacturing plant project report, the major raw materials for Metronidazole production include 2-Methylimidazole-2-Chloroethanol/Ethylene Oxide-Chloroform-Ethyl Acetate.

Manufacturing Process of Metronidazole

The extensive Metronidazole production cost report consists of the following industrial manufacturing process:

• Production from 2-Methylimidazole: This method of production involves the nitration of 2-methylimidazole, which results in the formation of 2-methyl-5-nitroimidazole. Then, the product obtained is further reacted with an excess of 2-chloroethanol or ethylene oxide to obtain 2-methyl-5-nitroimidazol-1-ethanol or Metronidazole as the product. It further undergoes purification processes that involve extraction with chloroform and recrystallization by using ethyl acetate to obtain pure Metronidazole as the desired product.

Metronidazole appears as a yellowish-white crystalline powder and is bitter. The molecular formula of the compound is C6H9N3O3, and its molecular weight is 171.15 g/mol. The pH of its saturated aqueous solution is about 6.5. It is available in the form of tablets, capsules, topical forms, and benzoate oral suspension. It belongs to the class of nitroimidazole antibiotics. This drug mainly targets anaerobic bacteria and damages bacterial DNA. The melting point and the boiling point of the compound is 158-160 °C and 405.4 °C, respectively. The density of the compound is 1.5 g/cm3, and its flash point is 199°C. Moreover, it was first used as medicine in 1960. Its tablet form should be stored in an air-tight container at a temperature less than 25 °C.