Miconazole Production Cost Reports

The report provides a detailed analysis essential for establishing a miconazole manufacturing plant. It encompasses all critical aspects necessary for miconazole production, including the cost of miconazole production, miconazole plant cost, miconazole production costs, and the overall miconazole manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a miconazole production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Miconazole is an FDA-approved antifungal medication for the treatment of skin and vaginal infections caused by dermatophytes and candida. It is used as a medicine for the treatment of mucocutaneouscandidiasis, which include oropharyngeal candidiasis, fungal infections of the throat, and other fungal skin infections. Moreover, the compound is often used as a treatment for athlete's foot, ringworm, and other fungal skin infections. It is used as a component in the manufacture of various antifungal creams, powders, and oral gels. Additionally, it is also used as a veterinary medicine for the treatment of skin infections in animals.

The market for miconazole is predominantly driven by its extensive usage in the treatment of candidal skin infections and vaginal yeast infections, which significantly boosts its demand in the medical and pharmaceutical industries. Its primary usage for the treatment of vaginal candidosis, acute internal mycoses, candida, and dermatophyte infections of the skin further enhances its demand in the medical industry. Moreover, its utilization as an active ingredient in antifungal creams, topical ointments, and oral thrush treatment for the treatment of fungal infections of the skin, mouth, and throat effectively accentuates its demand in the personal care, healthcare, and pharmaceutical industries.

Additionally, its application in the manufacture of animal health products to address fungal infections in animals remarkably fuels its demand in the veterinary medicine industry. Furthermore, several factors influence industrial miconazole procurement, such as the availability of raw materials, cost and pricing, compliance with pharmaceutical regulations, quality standards, technological advancements, environmental considerations, sustainability practices, distribution (including trading and shipping), logistics, safety standards, etc.

Raw Material for Miconazole Production

According to the Miconazole manufacturing plant project report, the major raw materials for Miconazole production include 2,4-Dichlorophenacylbromide- Imidazole-Sodium Borohydride-2,4-Dichlorobenzylbromide-Sodium Hydride.

Manufacturing Process of Miconazole

The extensive Miconazole production cost report consists of the following industrial manufacturing process:

• Production from 2,4-Dichlorophenacylbromide: This production process is initiated by reacting 2,4-dichlorophenacylbromide with imidazole to form 1-(2,4-dichlorobenzoylmethyl)-imidazole[2,4-dichloro-ω-(1-imidazolyl)-acetophenone], followed by the addition of sodium borohydride, which reduces its carbonyl group to produce 1-(2,4-dichlorophenyl)-3-(1-imidazolyl)-ethanol. Further, the hydroxyl group of the product is alkylated by 2,4-dichlorobenzylbromide in the presence of a strong base, like sodium hydride, to synthesize miconazole as the product.

Miconazole appears as an odorless, white, crystalline powder, which does not completely dissolve in water but is soluble in ethanol. It is a member of the class of imidazoles that act as a medicine for treating fungal infections. Its function is to kill the fungi and completely inhibit their growth by damaging their cell membrane. The molecular formula of the compound is C18H14Cl4N2O, and its molecular weight is 416.1 g/mol.

It is used in two forms- topically and by intravenous infusion. It is commonly sold under the brand name Monistat. The melting point of Miconazole is 159-163 °C. The IUPAC name of the compound is 1-[2-[(2,4-dichlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole.