Mometasone (Nasonex) Production Cost Reports

Healthcare

The report provides a detailed analysis essential for establishing a mometasone (Nasonex) manufacturing plant. It encompasses all critical aspects necessary for mometasone (Nasonex) production, including the cost of mometasone (Nasonex) production, mometasone (Nasonex) plant cost, mometasone (Nasonex) production costs, and the overall mometasone (Nasonex) manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a mometasone (Nasonex) production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Mometasone (Nasonex) is a kind of corticosteroid drug that is majorly known for its applications in the medical industry. It is extensively used as a medication for the treatment of asthma, pruritus, dermatitis, and nasal congestion. Moreover, it also finds its application as a nasal spray to prevent and treat symptoms of allergic rhinitis, including runny nose and sneezing. Additionally, the drug is also employed as an ointment or lotion as a treatment for various inflammatory skin diseases, which include dermatitis, psoriasis, etc., and as an inhaler to manage symptoms of asthma. It is often utilized in research activities for the development of new drug delivery mechanisms.

The market for mometasone (Nasonex) is majorly driven by its broad usage as a steroid medication for the treatment of allergic rhinitis, nasal polyps, and other inflammatory conditions, which remarkably increases its demand in the pharmaceutical industry. Moreover, its utilization in the form of an inhaler for the treatment of asthma or any inflammation in the airways further enhances its demand in the medical and pharmaceutical industries.

Additionally, its employment in the biotechnology and research & development industries for clinical studies and new drug formulations effectively amplifies its market growth. Furthermore, several factors influence industrial mometasone (Nasonex) procurement, such as the availability of raw materials (2-furoyl chloride-dichloromethane, etc.), cost and pricing, compliance with medical regulations, quality standards, technological advancements, environmental considerations, sustainability practices, distribution (including trading and shipping), logistics, safety standards, etc.

Raw Material for Mometasone (Nasonex) Production

According to the Mometasone (Nasonex) manufacturing plant project report, the major raw materials for Mometasone (Nasonex) production include 16α-methyl-1l,4,9(11)-pregnatriene-17α,21-diol-3,20-dione 21-acetate - 2-Furoyl Chloride-Dichloromethane - 4-Dimethylamino)pyridine.

Manufacturing Process of Mometasone (Nasonex)

The extensive mometasone (Nasonex) production cost report consists of the following industrial manufacturing processes:

  • Production via Acylation: This method of production is initiated by the acylation of 16α-methyl-1l,4,9(11)-pregnatriene-17α,21-diol-3,20-dione 21-acetate with 2-furoyl chloride in dichloromethane in the presence of 4-dimethylamino)pyridine to form 17α-furoate. Then, the obtained 17α-furoate was mixed in THF and added with 70% HClO4 in water, which facilitates the removal of an acetyl group to give hydroxyl ketone. Further, the hydroxyl group of this compound is replaced by chlorine by converting it to mesylate through the nucleophilic substitution of mesyl group by using LiCl in DMF. The obtained chloride compound is further reacted with 1,3-dichloro-5,5-dimethylhydantoin in water to produce mometasone furoate as the final product.
  • Production from Epoxide: This method of reaction involves the acidic hydrolysis of epoxide in water to give a diol. The obtained diol is further reacted with dry HCL in the presence of acetic acid, which results in the formation of mometasone furoate as the final product.

Mometasone (Nasonex) belongs to the class of medicines that are known as corticodteroids. The molecular formula of the compound is C22H28Cl2O4, and its molecular weight is 427.4 g/mol. The other names of the compound are Mometasone, Mometasona, and Mometasonum. Moreover, the melting point of the compound is 218-220°C, and it does not dissolve in water. The IUPAC name of the compound is (8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one. Additionally, the compounds have anti-inflammatory and dermatologic drug. This drug is available in the form of a topical formulation, lotion, and cream.

Product Details

Particulars Details
Product Name Mometasone (Nasonex)
Scope Manufacturing Process: Process Flow, Material Flow, Material Balance

Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation

Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital

Variable Cost: Raw Material, Utilities, Other Variable Costs

Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs

Financing Costs: Interest on Working Capital, Interest on Loans

Other Costs: Depreciation Charges, General Sales and Admin Cost
Currency US$ (Data can also be provided in the local currency)
Pricing and Purchase Options Basic: US$ 2499
Premium: US$ 3499
Enterprise: US$ 4799
Customization Scope The report can be customized as per the requirement of the customer
Post-Sale Analysts Report 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable
Delivery Format PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request)

How does our Mometasone (Nasonex) Production Cost Report Provide Exhaustive Data and Extensive Insights?

At Procurement Resource, we not only focus on optimizing the should cost of production for Mometasone (Nasonex) but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.

We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Mometasone (Nasonex) market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.

Key Questions Answered in This Report

  • What are the key requirements for setting up a mometasone (Nasonex) manufacturing plant?
  • How is mometasone (Nasonex) manufactured?
  • What is the process flow involved in producing mometasone (Nasonex)?
  • What are the raw material requirements and costs for producing mometasone (Nasonex)?
  • What is the total size of land required for setting up a mometasone (Nasonex) manufacturing plant?
  • What are the construction requirements for setting up a mometasone (Nasonex) manufacturing plant?
  • What are the machinery requirements for producing mometasone (Nasonex)?
  • What are the utility requirements and costs for producing mometasone (Nasonex)?
  • What are the manpower requirements for producing mometasone (Nasonex)?
  • What are the average salaries/wages of manpower working in a mometasone (Nasonex) manufacturing plant?
  • What are the packaging requirements and associated costs for mometasone (Nasonex)?
  • What are the transportation requirements and associated costs for mometasone (Nasonex)?
  • What are the capital costs for setting up a mometasone (Nasonex) manufacturing plant?
  • What are the operating costs for setting up a mometasone (Nasonex) manufacturing plant?
  • What should be the price of mometasone (Nasonex)?
  • What will be the income and expenditures for a mometasone (Nasonex) manufacturing plant?

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