Nebivolol (Bystolic) Production Cost Reports

Healthcare

The report provides a detailed analysis essential for establishing a nebivolol (Bystolic) manufacturing plant. It encompasses all critical aspects necessary for nebivolol (Bystolic) production, including the cost of nebivolol (Bystolic) production, nebivolol (Bystolic) plant cost, nebivolol (Bystolic) production costs, and the overall nebivolol (Bystolic) manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a nebivolol (Bystolic) production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Nebivolol (Bystolic) is a generic name for the medication that is widely used in the medical and pharmaceutical industries. It is majorly utilized for the treatment of hypertension or high blood pressure. It is also associated with reducing the risks of heart failure and improving its function. Moreover, it also finds its application as a medicine prescribed for its vasodilating properties to enhance blood flow to the heart and reduce the risk of fatal cardiovascular events in patients with certain heart conditions.

The market for nebivolol (Bystolic) is majorly driven by its broad usage as an anti-hypertensive medication to treat high blood pressure, which remarkably promotes its demand in the pharmaceutical industry. Additionally, its usage for the treatment of heart failure and promoting cardiovascular health further amplifies its demand in the medical and pharmaceutical industries. Furthermore, several factors influence industrial nebivolol (Bystolic) procurement, such as the availability of raw materials (6-Fluoro-4-oxo-4H-1-benzopyran-2-carboxylic acid, etc.), cost and pricing, compliance with medical and pharmaceutical regulations, quality standards, technological advancements, environmental considerations, sustainability practices, distribution (including trading and shipping), logistics, safety standards, etc.

Raw Material for Nebivolol (Bystolic) Production

According to the Nebivolol (Bystolic) manufacturing plant project report, the major raw material for Nebivolol (Bystolic) production includes 6-Fluoro-4-oxo-4H-1-benzopyran-2-carboxylic acid.

Manufacturing Process of Nebivolol (Bystolic)

The extensive nebivolol (Bystolic) production cost report consists of the following industrial manufacturing process:

  • Production via Catalytic Hydrogenation: This method of production is initiated by the catalytic hydrogenation of 6-fluoro-4-oxo-4H-1-benzopyran-2-carboxylic acid in the presence of Pd-C catalyst to form 6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid. Further, the obtained product is transformed into the corresponding ketone through the coupling reactions of carbonyldiimidazole with acids, followed by its reduction with bis-(2-methylpropyl)-aluminum hydride to give an aldehyde. Then, the obtained aldehyde is reacted with trimethylsulfoxonium iodide to synthesize oxiranyl chromane through the Corey–Chaykovsky reaction. Oxiranyl chromane is then subjected to reflux with benzylamine in ethanol, which facilitates the two ring-opening reactions to form a bis-product, followed by hydrogenation in the presence of a Pd-C catalyst to produce nebivolol as the desired product.

Nebivolol (Bystolic) belongs to the chromanes family and is regarded as a secondary amino molecule, diol, and secondary alcohol. Its molecular formula is C22H25F2NO4, and the molecular weight is 405.4 g/mol. Moreover, the IUPAC name of the compound is 1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2 -hydroxyethyl]amino]ethanol. The melting point of this drug is 223.0-228.0 degrees Celsius. It is a racemic combination of (S,R,R,R) and (R,S,S,S) enantiomers. It is regarded as the most potent β1-selective adrenoceptor antagonist that is currently approved for clinical use. This drug may have some side effects, including headache, rash, and sleeplessness.

Product Details

Particulars Details
Product Name Nebivolol (Bystolic)
Scope Manufacturing Process: Process Flow, Material Flow, Material Balance

Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation

Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital

Variable Cost: Raw Material, Utilities, Other Variable Costs

Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs

Financing Costs: Interest on Working Capital, Interest on Loans

Other Costs: Depreciation Charges, General Sales and Admin Cost
Currency US$ (Data can also be provided in the local currency)
Pricing and Purchase Options Basic: US$ 2499
Premium: US$ 3499
Enterprise: US$ 4799
Customization Scope The report can be customized as per the requirement of the customer
Post-Sale Analysts Report 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable
Delivery Format PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request)

How does our Nebivolol (Bystolic) Production Cost Report Provide Exhaustive Data and Extensive Insights?

At Procurement Resource, we not only focus on optimizing the should cost of production for Nebivolol (Bystolic) but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.

We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Nebivolol (Bystolic) market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.

Key Questions Answered in This Report

  • What are the key requirements for setting up a nebivolol (Bystolic) manufacturing plant?
  • How is nebivolol (Bystolic) manufactured?
  • What is the process flow involved in producing nebivolol (Bystolic)?
  • What are the raw material requirements and costs for producing nebivolol (Bystolic)?
  • What is the total size of land required for setting up a nebivolol (Bystolic) manufacturing plant?
  • What are the construction requirements for setting up a nebivolol (Bystolic) manufacturing plant?
  • What are the machinery requirements for producing nebivolol (Bystolic)?
  • What are the utility requirements and costs for producing nebivolol (Bystolic)?
  • What are the manpower requirements for producing nebivolol (Bystolic)?
  • What are the average salaries/wages of manpower working in a nebivolol (Bystolic) manufacturing plant?
  • What are the packaging requirements and associated costs for nebivolol (Bystolic)?
  • What are the transportation requirements and associated costs for nebivolol (Bystolic)?
  • What are the capital costs for setting up a nebivolol (Bystolic) manufacturing plant?
  • What are the operating costs for setting up a nebivolol (Bystolic) manufacturing plant?
  • What should be the price of nebivolol (Bystolic)?
  • What will be the income and expenditures for a nebivolol (Bystolic) manufacturing plant?

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