Nomegestrol Acetate Production Cost Reports

The report provides a detailed analysis essential for establishing a Nomegestrol Acetate manufacturing plant. It encompasses all critical aspects necessary for Nomegestrol Acetate production, including the cost of Nomegestrol Acetate production, Nomegestrol Acetate plant cost, Nomegestrol Acetate production costs, and the overall Nomegestrol Acetate manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Nomegestrol Acetate production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Nomegestrol Acetate (NOMAc) is an FDA-approved synthetic steroid hormone that finds its specific applications in the medical industry. It is widely utilized as an oral contraceptive and has quickly acquired acceptance in many countries for HRT/hormone replacement therapy. Moreover, it also finds its application as a medication for the treatment of menstrual cycle disorders, such as increased menstruation and various menopausal symptoms. It is also used for the treatment of certain diseases of the uterus. Additionally, it is often employed as an oral drug to treat several gynecological disorders, which include menstrual disturbances, dysmenorrhoea, and premenstrual syndrome.

The market for Nomegestrol Acetate is led by its industrial application as an oral contraceptive in various gynecological therapies and hormone replacement therapies, significantly boosting its demand in the medical and healthcare industries. Moreover, its utilization as an antigonadotropic agent for the treatment of menstrual disorders, painful menstruation, premenstrual syndrome, and symptoms associated with menopause further enhances its demand in the pharmaceutical industry. Furthermore, several factors impact industrial Nomegestrol Acetate procurement, such as the availability of raw materials (sodium acetate, etc.), cost and pricing, regulatory compliance, and maintenance of quality standards. Additionally, technological advancements, supplier relationships, sustainability practices, distribution (including trading and shipping), logistics, safety standards, etc., are also involved in shaping procurement techniques.

Raw Material for Nomegestrol Acetate Production

According to the Nomegestrol Acetate manufacturing plant project report, the major raw materials for Nomegestrol Acetate production include 17a-Acetoxy-6-methylene-19-norpregn-4-ene-3,20-dione-Ethanol-Sodium Acetate.

Manufacturing Process of Nomegestrol Acetate

The extensive Nomegestrol Acetate production cost report consists of the following industrial manufacturing process:

• Production via Isomerization: This method of production involves the process of isomerization in a mixture of solvents containing primary alcohols (preferably ethanol) at a temperature between 50°C and the boiling point of the solvent, which results in the formation of nomegestrol acetate. The process is initiated by the conversion of 17a-acetoxy-6-methylene-19-norpregn-4-ene-3,20-dione to 17a-acetoxy-6-methyl-19-norpregna-4,6-diene-3,20-dione (Nomegestrol-acetate) in a volume of two hundred fold ethanol, at a temperature between 50°C and the boiling point of the solvent, in the presence of palladium/carbon catalyst along with different auxiliary materials, like sodium acetate or water to obtain nomegestrol acetate as the final product.

Nomegestrol Acetate, also known as NOMAc, exists in the form of light yellow to white crystalline powder. The compound is a derivative of norpregnane. Moreover, the molecular formula of the compound is C23H30O4, and its molar mass is 370.5 g/mol. The compound is observed to have a potential endocrine-disrupting compound. The melting point of the compound is 177.0 to 181.0 °C. Additionally, the chemical name of the compound is 17-(Acetyloxy)-6-methyl-19-norpregna-4,6-diene-3,20-dione; 6-Methyl-17.alpha.-acetoxy-6-19-norprogesterone. It is generally stored in the temperature range between 2-8 °C.