Olmesartan Production Cost Reports
Healthcare
The report provides a detailed analysis essential for establishing an olmesartan manufacturing plant. It encompasses all critical aspects necessary for olmesartan production, including the cost of olmesartan production, olmesartan plant cost, olmesartan production costs, and the overall olmesartan manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating an olmesartan production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Olmesartan is a form of medication that is widely used for the treatment of high blood pressure. It is often called an angiotensin receptor blocker that widens the blood vessels in the body to make it easier for the heart to pump blood throughout the body. It also reduces the risk of heart attack or any fatal cardiovascular events. Moreover, it is often utilized in combination with other antihypertensive drugs, such as hydrochlorothiazide, to enhance its efficiency and reduce its side effects.
The market for Olmesartan is majorly led by its utilization as a medicine to treat hypertension or high blood pressure due to its blood pressure-lowering effects, which remarkably propels its demand in the medical and pharmaceutical industries. Moreover, its application as angiotensin II receptor blockers (ARBs) that help in relaxing and widening the blood vessels, which reduces the risk of heart failure or kidney disease, further boosts its demand in the medical and healthcare industries.
Furthermore, several factors influence industrial Olmesartan procurement, such as the availability and cost of production of Olmesartan's raw materials, cost and pricing, compliance with pharmaceutical regulations, quality standards, technological advancements, environmental considerations, sustainability practices, distribution (including trading and shipping), logistics, safety standards, etc.
Raw Material for Olmesartan Production
According to the Olmesartan manufacturing plant project report, the major raw materials for Olmesartan production include Diaminomaleonitrile-Trimethyl Orthobutyrate-Methyl Cyanide (CH3CN)-Toluene- Methylmagnesium Bromide-Lithium Hydroxide- Medoxomil- Aqueous Acetic Acid.
Manufacturing Process of Olmesartan
The extensive Olmesartan production cost report consists of the following industrial manufacturing process:
- Production from Imidazole-Dicarbonitrile: This method of production is initiated with the formation of imidazole-dicarbonitrile by the cyclocondensation of diaminomaleonitrile and trimethyl orthobutyrate, followed by heating in boiling methyl cyanide (CH3CN) and toluene. Further, the obtained dinitrile is hydrolyzed to a diacid.
It is converted into 4-hydroxyalkyl imidazole by reacting with methylmagnesium bromide, followed by alkylation with a biphenyl-tetrazolyl bromide derivative to add a biphenyl-tetrazole group to the product. Then, the obtained ester is further hydrolyzed with lithium hydroxide, followed by alkylation with medoxomil chloride to form trityl-protected Olmesartan. Then, the protective group from the product is removed with the help of 25% aqueous acetic acid to obtain the desired Olmesartan.
Olmesartan is an antihypertensive agent and is a synthetic biphenylyltetrazole. The molecular formula of the compound is C24H26N6O3, and its molar mass is 446.5 g/mol. The IUPAC name of the compound is 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid.
It appears as a light yellowish crystalline powder that is not readily soluble in water but dissolves to 20mM in DMSO. The melting point and the boiling point of the compound are 175-180°C and 800ºC, respectively. It is generally sold under the name Benicar. Its function is to inhibit substances that cause blood vessels to tighten, and thus, it helps relax the blood vessels and brings down the blood pressure.
Product Details
Particulars | Details |
---|---|
Product Name | Olmesartan |
Scope | Manufacturing Process: Process Flow, Material Flow, Material Balance Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital Variable Cost: Raw Material, Utilities, Other Variable Costs Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs Financing Costs: Interest on Working Capital, Interest on Loans Other Costs: Depreciation Charges, General Sales and Admin Cost |
Currency | US$ (Data can also be provided in the local currency) |
Pricing and Purchase Options | Basic: US$ 2499 Premium: US$ 3499 Enterprise: US$ 4799 |
Customization Scope | The report can be customized as per the requirement of the customer |
Post-Sale Analysts Report | 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable |
Delivery Format | PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request) |
Key Questions Answered in This Report
- What are the key requirements for setting up an olmesartan manufacturing plant?
- How is olmesartan manufactured?
- What is the process flow involved in producing olmesartan?
- What are the raw material requirements and costs for producing olmesartan?
- What is the total size of land required for setting up an olmesartan manufacturing plant?
- What are the construction requirements for setting up an olmesartan manufacturing plant?
- What are the machinery requirements for producing olmesartan?
- What are the utility requirements and costs for producing olmesartan?
- What are the manpower requirements for producing olmesartan?
- What are the average salaries/wages of manpower working in an olmesartan manufacturing plant?
- What are the packaging requirements and associated costs for olmesartan?
- What are the transportation requirements and associated costs for olmesartan?
- What are the capital costs for setting up an olmesartan manufacturing plant?
- What are the operating costs for setting up an olmesartan manufacturing plant?
- What should be the price of olmesartan?
- What will be the income and expenditures for an olmesartan manufacturing plant?
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