Phenacetin Production Cost Reports

The report provides a detailed analysis essential for establishing a phenacetin manufacturing plant. It encompasses all critical aspects necessary for phenacetin production, including the cost of phenacetin production, phenacetin plant cost, phenacetin production costs, and the overall phenacetin manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a phenacetin production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Phenacetin is a non-narcotic analgesic medicine that is widely used as a painkiller and fever-reducing drug. It is also used for the treatment of rheumatoid arthritis and other body conditions. Moreover, it is often utilized as a laboratory reagent to study the mechanism of similar analgesic compounds and various other research purposes. It is also used in certain hair dye preparations. Additionally, it finds its application as a veterinary medicine for the treatment of certain conditions in animals.

The market for phenacetin is predominantly driven by its extensive usage as an antipyretic and peripheral nervous system drug, as it helps in reducing pain and formulating other related compounds, which boosts its demand in the medical and pharmaceutical industries. Moreover, its usage as a component in the manufacture of dyes and pigments further enhances its demand in the dyeing and chemical manufacturing industries. Its employment in the treatment of animals remarkably accentuates its demand in the veterinary medicine industry.

Additionally, its usage as a lab reagent for experiments and research-related activities further amplifies its demand in the biotechnology and research & development industries. Furthermore, several factors influence industrial phenacetin procurement, such as the availability of raw materials, cost, and pricing, compliance with pharmaceutical regulations, quality standards, technological advancements, environmental considerations, sustainability practices, distribution (including trading and shipping), logistics, safety standards, etc.

Raw Material for Phenacetin Production

According to the Phenacetin manufacturing plant project report, the major raw materials for Phenacetin production include p-Nitrophenol-Ethyl Bromide-Sodium Hydroxide Solution; p-Nitrophenol-Sodium Hydroxide-Ethyl Sulfate-Glacial Acetic Acid; para-Phenetidine with Glacial Acetic Acid; para-Acetaminophen-Ethyl Bromide.

Manufacturing Process of Phenacetin

The extensive Phenacetin production cost report consists of the following industrial manufacturing processes:

• Production via Condensation: This production process is initiated in a sodium hydroxide solution, which involves condensation of p-nitrophenol with ethyl bromide. The product is further reduced with sodium sulfide, followed by acetylation with acetic anhydride to obtain Phenacetin as the final product.
• Production from p-Nitrophenol: This process involves the direct reaction of p-nitrophenol and sodium hydroxide with ethyl sulfate, followed by the reduction of nitrite to amine in the presence of iron and acid. Further, it undergoes acetylation with glacial acetic acid by boiling to produce phenacetin as the product.
• Production from para-Phenetidine: It involves the reaction of para-phenetidine with glacial acetic acid, followed by crystallization to obtain pure phenacetin.
• Production from para-Acetaminophen: The method involves the reaction of para-acetaminophen with ethyl bromide to produce phenacetin as the desired product.

Phenacetin appears as a fine white crystalline solid, which is odorless and tastes bitter. It is a member of the class of acetamides and aromatic ether. Its structure involves the attachment of one of its hydrogen to the nitrogen is substituted by a 4-ethoxyphenyl group. The molecular formula of the compound is C10H13NO2, and its molar mass is 179.22 g/mol. Moreover, it is less soluble in water and benzene but dissolves immediately in pyrimidine. It is also soluble in acetone. It is considered to be the first NSAID (Non-steroidal Anti-inflammatory Drug) on the market.