Rivaroxaban Production Cost Reports
Healthcare
The report provides a detailed analysis essential for establishing a Rivaroxaban manufacturing plant. It encompasses all critical aspects necessary for Rivaroxaban production, including the cost of Rivaroxaban production, Rivaroxaban plant cost, Rivaroxaban production costs, and the overall Rivaroxaban manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Rivaroxaban production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Rivaroxaban is an anticoagulant medication used in treating and preventing blood clots. It acts by blocking the activity of factor Xa, the clotting protein, that decreases thrombin levels and stops clot formation. It is used to inhibit stroke in individuals having non-valvular atrial fibrillation. Rivaroxaban treats deep vein thrombosis (DVT) and pulmonary embolism (PE) in individuals that experience recurrence after initial treatment. It also restraints DVT and PE in patients that recently had their hip, or knee replacement surgery, or those who are at risk due to decreased mobility. It is used in combination with aspirin to lower the chances of heart attack or stroke in elderly individuals having coronary artery disease or peripheral arterial disease. It comes in the list of WHO's essential medicines.
The procurement of Rivaroxaban is driven by several key factors. It is an effective anticoagulant therapy to prevent strokes and blood clots making it popular in clinical treatments. It's used to prevent vein thrombosis (DVT) and pulmonary embolism (PE) in patients who are at risk of stroke or heart attack due to immobilization or any recent surgery, making it a sought-after product. It is better than traditional anticoagulants, making it a preferred choice among healthcare providers. It is on WHO's list of essential medicines, making it a sought-after medication all over the world. Hence, its demand as an anticoagulant medication, along with its production prices, market prices, and logistics, directly influences industrial Rivaroxaban procurement across the globe.
Raw Material for Rivaroxaban Production
According to the Rivaroxaban manufacturing plant project report, the key raw materials used in the production of Rivaroxaban include (2-(Phenylamino) ethan-1-ol)-Chloroacetyl Chloride-Sodium Hydroxide-Ethanol-Nitric Acid-Sulfuric Acid-Palladium-Methanol-Epoxide-Carbonyldiimidazole-Tetrahydrofuran-Methylamine-Chlorothiophene Carboxylic Acid-Thionyl Chloride-Potassium Carbonate.
Manufacturing Process of Rivaroxaban
The extensive Rivaroxaban production cost report consists of the following major industrial manufacturing process:
- From 2-(Phenylamino) ethan-1-ol, Chloroacetyl Chloride, Sodium Hydroxide, Ethanol, Nitric Acid, Sulfuric Acid, Palladium, Epoxide, Carbonyldiimidazole, Tetrahydrofuran, Methylamine, Chlorothiophene Carboxylic Acid, Thionyl Chloride, and Potassium Carbonate: The manufacturing process for Rivaroxaban is a multi-step process. First, 2-(Phenylamino) ethan-1-ol is reacted with chloroacetyl chloride in the presence of sodium hydroxide and ethanol, forming a morpholine ring. This compound is then nitrated using nitric and sulfuric acids. After that, the nitro group is reduced to an amine by hydrogenation with palladium as a catalyst. This compound is further reacted with an epoxide in refluxing methanol to open the epoxide ring. After that, it goes through cyclization with carbonyldiimidazole in tetrahydrofuran, displacing the imidazole group with methylamine. Finally, it is coupled with chlorothiophene carboxylic acid using thionyl chloride in toluene, treated with potassium carbonate forming Rivaroxaban. After purification, the final product obtained is Rivaroxaban.
Rivaroxaban is a white to off-white crystalline powder. It has a molecular formula of CHClNOS and a molecular weight of 435.9 g/mol. It is slightly soluble in water but more soluble in organic solvents. It has a melting point of 228-229°C. It has a log P value of 2.5, making it moderately lipophile. It has a topological polar surface area of 116 Ų. It works as a direct inhibitor of factor Xa, reducing the risk of thromboembolic events. These physical and chemical properties make it an effective anticoagulant medication to be used in various applications.
Product Details
| Particulars | Details |
|---|---|
| Product Name | Rivaroxaban |
| Scope | Manufacturing Process: Process Flow, Material Flow, Material Balance Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital Variable Cost: Raw Material, Utilities, Other Variable Costs Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs Financing Costs: Interest on Working Capital, Interest on Loans Other Costs: Depreciation Charges, General Sales and Admin Cost |
| Currency | US$ (Data can also be provided in the local currency) |
| Pricing and Purchase Options | Basic: US$ 2499 Premium: US$ 3499 Enterprise: US$ 4799 |
| Customization Scope | The report can be customized as per the requirement of the customer |
| Post-Sale Analysts Report | 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable |
| Delivery Format | PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request) |
How does our Rivaroxaban Production Cost Report Provide Exhaustive Data and Extensive Insights?
At Procurement Resource, we not only focus on optimizing the should cost of production for Rivaroxaban but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.
We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing Rivaroxaban market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.
Key Questions Answered in This Report
- What are the key requirements for setting up a Rivaroxaban manufacturing plant?
- How is Rivaroxaban manufactured?
- What is the process flow involved in producing Rivaroxaban?
- What are the raw material requirements and costs for producing Rivaroxaban?
- What is the total size of land required for setting up a Rivaroxaban manufacturing plant?
- What are the construction requirements for setting up a Rivaroxaban manufacturing plant?
- What are the machinery requirements for producing Rivaroxaban?
- What are the utility requirements and costs for producing Rivaroxaban?
- What are the manpower requirements for producing Rivaroxaban?
- What are the average salaries/wages of manpower working in a Rivaroxaban manufacturing plant?
- What are the packaging requirements and associated costs for Rivaroxaban?
- What are the transportation requirements and associated costs Rivaroxaban?
- What are the capital costs for setting up a Rivaroxaban manufacturing plant?
- What are the operating costs for setting up a Rivaroxaban manufacturing plant?
- What should be the price of Rivaroxaban?
- What will be the income and expenditures for a Rivaroxaban manufacturing plant?
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