Sulfanilamide Production Cost Reports

The report provides a detailed analysis essential for establishing a Sulfanilamide manufacturing plant. It encompasses all critical aspects necessary for Sulfanilamide production, including the cost of Sulfanilamide production, Sulfanilamide plant cost, Sulfanilamide production costs, and the overall Sulfanilamide manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Sulfanilamide production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Sulfanilamide is an antibacterial agent mainly used in the treatment of vaginal infections such as vulvovaginitis caused by Candida albicans. It functions as a sulfonamide antibiotic by inhibiting bacterial growth through competitive inhibition of the enzyme dihydropteroate synthase, which is essential for folic acid synthesis in bacteria. It is mainly used in topical formulations. Additionally, Sulfanilamide has been utilized in various medical applications, such as the treatment of urinary tract infections and as part of first-aid kits for preventing infections.

The market demand for Sulfanilamide is majorly driven by its application as an antibacterial agent. Its function to produce antibacterial drugs for treating bacterial infections, mainly urinary tract infections, pneumonia, and streptococcal infections, which elevates its demand in the medical and pharmaceutical industries. The global rise in the focus on antimicrobial resistance boosts the demand for effective sulfa drugs, such as sulfanilamide-based formulations.

The rising incidence of bacterial and parasitic diseases, mainly in developing regions, fuels the market for sulfanilamide-based treatments. Its function to treat bacterial infections in livestock, poultry, and pets, contributes to its demand in the veterinary industry. Its function as an intermediate to produce other sulfa drugs and dyes, as well as in the synthesis of azo dyes, pesticides, and other industrial chemicals, further promotes industrial Sulfanilamide procurement.

Raw Material for Sulfanilamide Production

According to the Sulfanilamide manufacturing plant project report, the various raw materials for Sulfanilamide production include acetanilide-chlorosulfonic acid.

Manufacturing Process of Sulfanilamide

The extensive Sulfanilamide production cost report consists of the following major industrial manufacturing process:

• Production from acetanilide: The manufacturing process of Sulfanilamide initiates with the reaction of acetanilide with chlorosulfonic acid at 40-50 degrees Celsius. The mixture is then cooled, slowly added to water for acid decomposition, precipitated at the same time, dried, and filtered to obtain p-acetaminobenzenesulfonyl chloride. The resultant compound is subjected to ammoniation. The amination temperature is controlled at 40-45 degrees Celsius. The reaction produces p-acetylaminobenzene sulfonamide. The compound is hydrolyzed and acidified to produce Sulfanilamide as the final product.

Properties of Sulfanilamide

Sulfanilamide is a white to faintly beige crystalline powder having the molecular formula C66H88N22O22S, known for its role as a sulfonamide antibiotic. It has a density of 1.08 g/cm³ and a melting point in the range of 164.5 - 166.5 degrees Celsius. It is slightly soluble in cold water (7.5 g/L at 25 degrees Celsius) and more soluble in boiling water and various organic solvents. It has a pKa of 10.65, which indicates its acidic properties. It absorbs light at a maximum wavelength of 257 nm in water. It is utilized in the pharmaceutical industry, mainly as a precursor to synthesize various sulfonamide antibiotics.