Vilazodone Production Cost Reports

The report provides a detailed analysis essential for establishing a Vilazodone manufacturing plant. It encompasses all critical aspects necessary for Vilazodone production, including the cost of Vilazodone production, Vilazodone plant cost, Vilazodone production costs, and the overall Vilazodone manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Vilazodone production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Vilazodone is used for the treatment of severe forms of depression. It works by acting as a partial agonist for the serotonin receptor and a selective serotonin reuptake inhibitor (SSRI). It targets the 5-HT (5-hydroxytryptamine) and 5-HT1A receptors. It is used as an antidepressant drug to treat several conditions related to depression. It increases the levels of serotonin in the brain and activates the serotonin receptors. It can also be used to treat anxiety in patients. Thus, it finds its applications in the pharmaceutical and medical industries.

The procurement of Vilazodone is influenced by its use as an antidepressant drug in the pharmaceutical and medical industries. It is used to treat conditions related to severe depression. The global demand for Vilazodone is directly affected by the major depressive disorders that are becoming more common in recent times. Its use in treating conditions such as anxiety, apart from major depressive disorders, increases its market. It is known for showing fewer side effects, such as fewer sexual side effects and weight gain, as compared to other drugs, thus increasing its demand.

Due to the increasing awareness among patients about mental health, there has been an increase in demand for this drug. Also, the increase in healthcare facilities increases the market growth for Vilazodone. Overall, the industrial Vilazodone procurement is influenced by its application in the pharmaceutical and medical industries to treat conditions related to severe depression, the aging population, increasing cases of major depressive disorders, its use in conditions such as anxiety, fewer side effects, healthcare and technological advancements, cost-effectiveness, market dynamics, logistics and distribution, and regulatory approvals.

Raw Material for Vilazodone Production

According to the Vilazodone manufacturing plant project report, the key raw materials used in the production of Vilazodone include 4-cyanoaniline - 5-bromo-2-hydroxybenzaldehyde.

Manufacturing Process of Vilazodone

The extensive Vilazodone production cost report consists of the following major industrial manufacturing process:

• Production from 4-cyanoaniline and 5-bromo-2-hydroxybenzaldehyde: The manufacturing process of Vilazodone involves several key steps. Firstly, 4-cyanoaniline is diazotized to create the intermediate (3-(4-chlorobutyl)-1H-indole-5-carbonitrile), followed by Fisher indole cyclization with 6-chlorohexanal. Then, another intermediate, 5-(piperazin-1-yl)benzofuran-2-carboxamide is produced by the aromatic nucleophilic substitution of 5-bromobenzofuran-2-carboxamide with piperazine. In the final step, the two intermediates undergo nucleophilic substitution reaction by treatment with Et3N/K2CO3, to yield Vilazodone.

Vilazodone, commercially known as Viibryd, is a white to off-white powder, having the molecular formula C26H27N5O2 and a molecular weight of 441.5 g/mol. Its melting point is in the range 227-279 °C. Its solubility is 1.23e-01 g/L. It is soluble in organic solvents such as DMSO and dimethyl formamide. It is sparingly soluble in aqueous buffers. It is stable under normal handling conditions. It can release toxic gases after decomposition. It targets the 5-HT (5-hydroxytryptamine) and 5-HT1A receptors and elevates the levels of serotonin in the brain. It is utilized in the treatment of Major depressive disorders. It is also used to treat anxiety in patients.