Vortioxetine Hydrobromide Production Cost Reports

The report provides a detailed analysis essential for establishing a Vortioxetine hydrobromide manufacturing plant. It encompasses all critical aspects necessary for Vortioxetine hydrobromide production, including the cost of Vortioxetine hydrobromide production, Vortioxetine hydrobromide plant cost, Vortioxetine hydrobromide production costs, and the overall Vortioxetine hydrobromide manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Vortioxetine hydrobromide production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Vortioxetine hydrobromide is formed by reacting Vortioxetine with hydrobromic acid. It is utilized to treat serious depressive illness. It functions as a serotonergic antagonist, anxiolytic, antidepressant, and serotonergic agonist. It is used to treat major depressive disorders by modulating one or more serotonin receptors and inhibiting the reuptake of serotonin. Due to its anxiolytic qualities, vortioxetine may be used to treat Generalized Anxiety Disorder (GAD). It is a derivative of piperazine functioning as 5-HT3 receptor antagonist, 5-HT1A receptor agonist, and serotonin reuptake inhibitor. It is applied in the management of depression and anxiety. Thus, it finds its application in the pharmaceutical and medical industries.

The procurement of Vortioxetine hydrobromide is influenced by its application in the pharmaceutical and medical industries as an antidepressant drug used to treat major depressive disorders. The need for Vortioxetine hydrobromide is increasing as cases of MDDs are on the rise. It witnesses a significant demand from the aging population as they are more likely to be affected by depressive disorders and anxiety. Because of its distinct mode of action, which involves modulating several serotonin receptors and inhibiting serotonin reuptake, Vortioxetine hydrobromide is well-known.

Its wide range of efficacy increases its demand by making it appropriate for a variety of patients, including those who might not react to conventional SSRIs or SNRIs. Overall, the industrial Vortioxetine hydrobromide procurement is influenced by its application in the pharmaceutical and medical industries as an antidepressant drug to treat major depressive disorders, the increasing cases of MDDs, the aging population, a wide range of applications, distinct mode of action, its use with other drugs, along with research and development, rising awareness about mental health, cost-effectiveness, and regulatory approvals.

Raw Material for Vortioxetine Hydrobromide Production

According to the Vortioxetine hydrobromide manufacturing plant project report, the key raw material used in the production of Vortioxetine hydrobromide include 2,4-Dimethylbenzenethiol.

Manufacturing Process of Vortioxetine Hydrobromide

The extensive Vortioxetine hydrobromide production cost report consists of the following major industrial manufacturing process:

• Production from 2,4-Dimethylbenzenethiol: The manufacturing process of Vortioxetine hydrobromide involves a three-step process. It begins with the use of a palladium catalyst and a base to form a thioether bond between 2,4-Dimethylbenzenethiol and o-iodobromobenzene to form an intermediate. This intermediate is then subjected to amination in the presence of piperazine, creating a piperazine-linked intermediate. In the final step, this intermediate is then treated with hydrobromic acid at ambient temperature to form Vortioxetine hydrobromide.

Vortioxetine hydrobromide, commercially known as Trintellix, is a hydrobromide of Vortioxetine. Its molecular formula is C18H23BrN2S, and it has a molecular weight of 379.4 g/mol. Its IUPAC name is 1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine;hydrobromide. Its water solubility is 0.00362 mg/mL. Its log P value is 4.51. Its pKa value is 8.85. Vortioxetine hydrobromide is prepared by the reaction of Vortioxetine with hydrobromic acid at ambient temperature. It is an antidepressant medication used to treat major depressive disorders.