Trimethoprim Production From Gallic Acid
Production Cost Report | Healthcare
Details: Germany - based plant Q2 2024 | From $ USD
This report proffers the thorough economics of trimethoprim production from Gallic Acid. The preparation process begins with the chemical reaction between gallic acid and dimethyl sulfate that results in the formation of 3,4,5-trimethoxy benzoic acid as an intermediate product. The intermediate is further treated with hydrazine hydrate and potassium ferrocyanide and reduced to 3,4,5-trimethoxy benzaldehyde. The process is then followed by a complex reaction between 3,4,5-trimethoxy benzaldehyde, with beta morpholine acrylonitrile (which is obtained by reacting morpholine and acrylonitrile), and then treating its product with aniline and hydrochloric acid. It is then reacted with guanadine nitrate and results in the formation of trimethoprim as the end product.
Top Producers of Trimethoprim
- Alphapharm
- Ipca Laboratories
- GlaxoSmithKline
- Shilpa Medicare Limited (SML)
- Kojar
Feedstock for Trimethoprim
Trimethoprim is a chemical compound prepared by using gallic acid, along with dimethyl sulfate, hydrazine hydrate, potassium ferrocyanide, morpholine, acrylonitrile, aniline, hydrochloric acid, and guanadine nitrate as some of its major feedstock. The procurement of trimethoprim is prominently influenced by different factors, including the availability of its feedstock (including gallic acid, aniline, hydrochloric acid, morpholine, etc., for trimethoprim production), with its supply chain stability, production cost, and variations in market prices, etc.
Moreover, other factors, including the demand for trimethoprim in the pharmaceutical and healthcare sectors, the logistics and transportation activities, along with governmental and financial factors altogether, impact its procurement all over the world.
The project economic analysis provided in the report discusses a Germany-based plant:
- Manufacturing Process
- Process Flow
- Material Flow
- Material Balance
- Raw Material and Product's Specifications
- Raw Material Consumption
- Product and Co-Product Generation
- Capital Investment
- Land and Site Cost
- Offsites/Civil Works
- Equipment Cost
- Auxiliary Equipment Cost
- Contingency
- Engineering and Consulting Charges
- Working Capital
- Variable Cost
- Raw Material
- Utilities
- Fixed Cost
- Labor Requirement & Wages
- Overhead Expenses
- Maintenance Charges
- Financing Costs
- Interest on Working Capital
- Interest on Loans
- Depreciation Charges
- General Sales and Admin Costs
- Production Cost Summary
Report Content
Key Process Information
Evaluation of significant technical parameters along with process descriptions such as:
- Consumption of Raw Material
- Product Creation
- Block Flow Diagram
- Description of the Manufacturing Facility
Utilities Consumption
Evaluation of utilities consumed during the entire process based on:
- Consumption per unit of product generated
- Utility cost split and share of each utility in the total cost
Process Flow Diagram
Representation of various operations involved including:
- Step-wise process
- Utility consumption in each operation
Capital Cost Analysis
In-depth analysis of costs involved in setting up a new manufacturing unit, including:
- Cost of Building a Process Unit
- Cost of Setting Up the Infrastructure
- Working Capital
- Commissioning & Start-Up of the Plant
Implementation Schedule
Time frame of the project design, which includes:
- Plant Start-Up
- Plant Construction
- Engineering Fundamentals
- Raw Material Procurement
Construction Cost Details
Detailed analysis of costs involved in the operation of various functional units in the process unit and infrastructure.
Operating Cost Analysis
Evaluation of costs associated with the production of the final product, namely:
- Procurement of Raw Materials
- Consumption of Utilities
- Fixed Costs
- Depreciation
Economic Analysis
Analysis of the way in which process economics are impacted by plant capacity.
- Construction Cost
- Working Capital
- Fixed and Variable Operating Costs
- Corporate Overhead
- Depreciation
Customized Analyses
Detailed cost estimates of any industrial plant depending on your requirements, including plant capacity and location as per the need.
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