Isoniazid Production Cost Reports

The report provides a detailed analysis essential for establishing an Isoniazid manufacturing plant. It encompasses all critical aspects necessary for Isoniazid production, including the cost of Isoniazid production, Isoniazid plant cost, Isoniazid production costs, and the overall Isoniazid manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating an Isoniazid production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Isoniazid is a synthetic derivative of nicotinic acid that is used for the treatment of mycobacterium tuberculosis infection. It works by stopping the synthesis of mycolic acid, which is important for bacterial cell walls.  It is utilized as an antibiotic for the treatment and prevention of tuberculosis. It is also utilized to treat atypical mycobacterial infections and employed in combination therapies. It is available in various dosage forms that include tablets, syrup, and injectable forms. It is an important component of multiple-drug programs but requires careful monitoring due to potential side effects like liver toxicity.

The isoniazid market is mainly driven by the increasing incidence of tuberculosis around the world. Its extensive use not only in the treatment of active TB but also in the prevention of latent TB infections drives its demand. New government initiatives that lead to improved healthcare facilities further support its market growth. Advancement in research and development for new formulations and combination therapies involving isoniazid drives its demand and expands its applications. Improvements in drug delivery systems have made it an important drug for treating diseases like TB. Overall, industrial Isoniazid procurement is influenced by its usage in the pharmaceutical industry, along with other factors that drive its growth around the world.

Raw Material for Isoniazid Production

According to the Isoniazid manufacturing plant project report, the key raw materials used in the production of Isoniazid include 4-Cyanopyridine-Methanol-Sodium Hydroxide-Hydrazine Hydrate.

Manufacturing Process of Isoniazid

The extensive Isoniazid production cost report consists of the following major industrial manufacturing process:

• Production From 4-Cyanopyridine, Methanol, Sodium Hydroxide, and Hydrazine Hydrate: The production of Isoniazid involves a two-step process. First, 4-cyanopyridine goes through hydrolysis in a mixture of methanol and water in the presence of sodium hydroxide, converting it into isonicotinamide. After that, isonicotinamide reacts with hydrazine hydrate, forming Isoniazid as the final product.

Isoniazid has a molecular formula of C6H7N3O with a molecular weight of 137.14 g/mol. It is a white crystalline powder that is odorless. Its melting point is in the range of 171–173 °C with a boiling point of 252 °C. Its density is around 1.262 g/cm³ with a refractive index value of 1.691. It shows limited solubility in water but slight solubility in chloroform and very slight solubility in ether. It gets affected by exposure to air and light, and its chemical reactivity includes the potential to form condensation products when mixed with certain sugars like fructose, glucose, and sucrose. Its side effects include loss of appetite, nausea, vomiting, dark urine, weakness, etc.