Ketoconazole Production Cost Reports

The report provides a detailed analysis essential for establishing a Ketoconazole manufacturing plant. It encompasses all critical aspects necessary for Ketoconazole production, including the cost of Ketoconazole production, Ketoconazole plant cost, Ketoconazole production costs, and the overall Ketoconazole manufacturing plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Ketoconazole production plant. These encompass manufacturing processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Ketoconazole is a medication that is used to treat various fungal infections and is used in dermatology, pharmaceutical, and healthcare sectors. It is used to treat various yeast and fungal infections. It is utilized to treat conditions such as ringworm, athlete’s foot, yeast infections of the skin, and many other infections. It works by stopping the synthesis of ergosterol, which is important for fungal cell membrane integrity, preventing fungal growth. It is also used in various other formulations and in managing other diseases like prostate cancer and Cushing syndrome. However, it has certain side effects like blistering, hepatotoxicity, nausea, vomiting, and tongue discoloration.

Industrial Ketoconazole procurement is mainly influenced by its usage in treating various fungal diseases. The growing cases of fungal and yeast infections boost its market growth. Its utilization in the treatment of a range of other diseases contributes to its demand.  Growing awareness towards timely treatment of fungal infections also contributes to its market growth. The development of dermatological and pharmaceutical industries, along with technological advancements, further drives its market growth. Altogether, these factors contribute to the growth of the ketoconazole market across the world and govern its overall procurement around the globe.

Raw Material for Ketoconazole Production

According to the Ketoconazole manufacturing plant project report, the key raw materials used in the production of Ketoconazole include Cis Tosylate-(N-Acetyl-(4-Hydroxy Phenyl) Piperazine)-Dimethyl Sulfoxide.

Manufacturing Process of Ketoconazole

The extensive Ketoconazole production cost report consists of the following major industrial manufacturing process:

• Production From Cis Tosylate, N-Acetyl-(4-Hydroxy Phenyl) Piperazine, Dimethyl Sulfoxide: The manufacturing process of Ketoconazole involves a condensation reaction. In this process, Cis Tosylate reacts with N-Acetyl-(4-Hydroxy phenyl) Piperazine in the presence of acetone and dimethyl sulfoxide, forming an enantiomer of ketoconazole. After this, methanol is added to get Ketoconazole as the final product.

Ketoconazole has a molecular formula of C26H28Cl2N4O4 and molecular weight of 531.43 g/mol. It appears as colorless crystals with melting points in the range of 148 °C to 152 °C and a boiling point of 753.4 °C. Its density is around 1.4046 g/cm³, and it is soluble in water depending upon the pH and dissolves in methanol, DMSO, ethanol, and chloroform. It exhibits moderate lipophilicity indicating its affinity for organic solvents. Also, its ability to engage in hydrogen bonding potentially influences its medicinal properties. It decomposes to emit toxic fumes of nitrogen oxides and hydrogen chloride.